In this section we have spot diagnoses posted on a daily basis since June 2010, now over 1700! You can review the archived cases and read the suggested diagnoses by users and the final comment by Dr Uma Sundram, the Editor-in-Chief and main spot diagnosis host. Case are uploaded each week day by 10 a.m. UK time with the correct diagnosis will generally be posted at 8 p.m. UK time. Why not view the most recent spot diagnosis and proffer a diagnosis?

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Case Number : Case 3415 - 2 October 2019 Posted By: Dr. Hafeez Diwan

Please read the clinical history and view the images by clicking on them before you proffer your diagnosis.
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14 year-old male with recently enlarging chin nodule.

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User Feedback


Difficult case: the first 2 figures are compatible with myofibroma. The last 2 figures don't really show the characteristic biphasic architecture of myofibroma.

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Meenakshi Batrani

Posted

Top portion resembles myofibroma, the lower portion along the subcutis could be a myopericytoma (which can be vascular or solid type). There is lot of overlap between perivascular myoid tumors with some showing features of both. 

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Dr. Hafeez Diwan

Posted

Portions of this look like myofibroma.  Around the myofibroma there was dense CD34 positivity (in the portion represented by the lower 2 images).  I called this myofibroma with associated CD34 positive spindle cell neoplasm.  The 17:22 translocation was negative.

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