Case Number : Case Number : Case 1902 - 12 Sept - Dr Richard Carr Posted By: Guest

Dear All! Good morning!

We have now added the immuno proflie to Richard's case. 

Many thanks to Richard for the time he takes to provide the educational cases

DermpathPRO Admin 

Myxoid variant of DFSP.

I found it challenging. I am happy to have put DFSP in my differential as Vincenzo. IHC is mandatory here (CD34, S-100, EMA, etc) and even molecular tets for demonstrating COL1A1-PDGFB. For me the variant here is rather plaque like/atrophic with myxoid areas, particular findings are the localization (mainly deep dermis) and clinical impression (vascular malformation??) 

"For me the variant here is rather plaque like/atrophic with myxoid areas, particular findings are the localization (mainly deep dermis)"...

Agree with you Raul! I would have preferred named this myxojaline variant, but don't know this. Maybe sclerosing could be a better adjective...

Agree with atrophic & sclerotic DFSP. I only did the CD34 given the H&E features. Well done chaps. Quality responses.