Case Number : CT0029 Adam_Bates

I think of spindle cell lipoma or angiolipoma but since the lesions clinically are multiple and considering the young age , clinically I think this favours more angiolpoma ( both variants of lipomas show myxoid areas as shown in fig 4 I HOPE I AM ON THE RIGHT TRACK
 

Beautifully illustrated case of fibrous hamartoma of infancy!
 

Fibrous hamartoma of infancy. Usually it is a single lesion. Multiple tumors are rare. For the multiplicity, I woundered about myofibromatosis but the configuration is totally different. So it is an interesting case of multiple fibrous hamartomas of infancy.
 

I agreee with Fibrous hamartoma of infancy. If you see case 94, october 2010, you can see some differences with the spindle cell lipoma, like the primitive mesenchymal cells in well defined nests we see here. The age is also different between the two disease.
 

I would prefer call this lipofibromatosis instead of fibrous hamartoma of infancy because lesions are multiple rather than solitary and occur in the arm rather than the shoulder. Both share the microscopic picture of mature fat interspersed by streaks of cellular fibrous tissue.
What bothers me is a feature that is supposed to be exclusively found in fibrous hamartoma of infancy, I mean those small organoid spherules of primitive round cells.

Multiple fibrous hamartomas of infancy. Enzinger could have been exulted with it. Myofibroblasts are the culprit cells apparently; so, myofibroblastoma family traits are present in this lesion. Heard of a case with hypertrichosis.