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Building Blocks of Dermatopathology

BAD DermpathPRO Learning Hub: Diagnostic Clues

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Case Number : CT0077 Adam_Bates

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22/M, scalp biopsy. Marked perifollicular erythema ?folliculitis decalvans ?lichenplanopilaris


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Adam_Bates

Posted

I'm guessing Langerhans cell histiocytosis.  Need IHC, though.

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Adam_Bates

Posted

I think of LCH ,too. CD1a will help.
 

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Adam_Bates

Posted

Nice and typical clinical presentation with an infectious like pattern on the scalp.

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Adam_Bates

Posted

Folliculocenteric LCH, marvelous case :-)
 

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Adam_Bates

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Yes this is folliculocentric langerhans cell histiocytosis. It is quite an unusual pattern of LCH as most localised forms of LCH show diffuse demal infiltrate of Langerhans cells and present as solitary nodule or papules. This case had an exclusive folliculocentric pattern and hence the clinical impression of ?folliculitis decalvans ?LPP...the histological diagnosis came as quite a surprise to the dermatologists. The patient has no other lesions and is well otherwise. See link below for a strikingly similar case report. http://www.ncbi.nlm.nih.gov/pubmed/15024194
 

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