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Building Blocks of Dermatopathology

BAD DermpathPRO Learning Hub: Diagnostic Clues

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Case Number : CT0109 Adam_Bates

Please read the clinical history and view the images by clicking on them before you proffer your diagnosis.
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Female 37 years, tender erythematous plaques on arms.


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Adam_Bates

Posted

Sweet's syndrome with marked subepidermal oedema
 

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Adam_Bates

Posted

Sweet syndrome
 

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Adam_Bates

Posted

Sweet syndrome... In the third picture, I can see besides neutrophils other mononuclear cells with some atypia. Could be Sweet syndrome associated to mieloid leukemia?
 

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Adam_Bates

Posted

AFND (Sweets syndrome)
 

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Adam_Bates

Posted

Sweet's syndrome ddx:rheumatoid neutrophilic dermatosis
 

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Adam_Bates

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As I have to go out this am, I am giving the answer early. You are all correct. The diagnosis is Sweet's syndrome. There may well be atypical cells in the infiltrate. Unfortunately, I do not have any information about the patient's hematological status. The subepidermal edema is very marked in this example and in some cases, blisters develop which may result in confusion with neutrophil-rich subepidermal blistering conditions.
 

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