Case Number : Case 40 Posted By: Guest

Phillip McKee - Overseas consultations (USA) Wrote:

Good morning all. You are all agreed on the diagnosis. There isn't really any point in not giving the final diagnosis as you are all correct- chondroid syringoma (mixed tumor). It was a primary in the skin. Well done, all of you.

Submitted on 04/08/2010 14:34
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Richard Carr - Warwick (UK) Wrote:

If this is not a chondroid syringoma (benign mixed tumour) my hat must get eaten!

Submitted on 04/08/2010 12:24
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Ivon - (UK) Wrote:

Beautiful website. I would also go for chondroid syringoma

Submitted on 04/08/2010 11:19
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Marcela Saeb Lima - MSL Dermatopato (Mexico City) Wrote:

Good morning! Chondroid syringoma. As usual lovely pic!

Submitted on 04/08/2010 11:09
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Rachel Hall - (Manchester) Wrote:

I agree that this is a chondroid syringoma, but exclude salivary origin of pleomorphic adenoma, depending on site

Submitted on 04/08/2010 09:43
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Eman El-Nabarawy - Dermatology Department,Faculty of Medicine, Cairo university. (Egypt.) Wrote:

Tubular,branching,lumina , duct like structures suggestive of eccrine differentiation, lined by 2 layers of cells, with marked variation in the size and shape in a basoplilic abundant chondroid stroma.Chondroid syringoma (mixed tumor of the skin. Amazing wondeful picture. Thanks Dr Mckee.

Submitted on 04/08/2010 06:15
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Mona Abdel-Halim - Dermatology Department, Faculty of Medicine, Cairo University (Egypt) Wrote:

I was thinking in this section all night. Actuall I could not sleep well! Although I did not read about paillary projections in chondroid syringoma, I have to admit that the bluish chondroid and myxoid stroma here is outstanding. I will consider chondroid syringoma but will still think of digital papillary adenocarcinoma as a ddx.

Submitted on 04/08/2010 06:05
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Mona Abdel-Halim - Dermatology Department, Faculty of Medicine, Cairo University (Egypt) Wrote:

Well, my first impression when I looked at this image was chondroid syringoma due to the bluish stroma that look somewhat chondroid in some areas. However, I can see that the tumor is mainly made of tubuloalveolar and ductal structures, some of them show papillary projections. Also crebriform areas are seen. Esinophilic secretory material is seen in some glandular lumina. I think what I percieved as chondroid syringoma could be areas of dense hyalinized collagen. Thin fibrous septa are seen in the rest of the stroma. I think this could be digital papillary adenocarcinoma.

Submitted on 04/08/2010 00:32
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Juan Carlos Garcés - Hospital Oncológico / Hospital Luis Vernaza (Guayaquil Ecuador) Wrote:

Good evening... chondroid syringoma.. If it is a biopsy from lip: Mixed tumor of salivary gland looks exactly the same

Submitted on 04/08/2010 00:27
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Yvonne Bury - (UK) Wrote:

A nodular and circumscribed lesion with epithelial and myoepithelial cells in abundant chondromyxoid stroma. I think this is a chondroid syringoma. PS: I really like the longer posts with lively discussion on this website.

Submitted on 04/08/2010 00:08
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