Case Number : Case 47 Posted By: Guest

Phillip McKee - Overseas consultations (USA) Wrote:

Well done. It is a beautiful example of leishmaniasis. Many thanks to all of you who have contributed comments this week. Have a wonderful weekend and I'll see you all on Monday

Submitted on 13/08/2010 21:34
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Donald Gates - (US) Wrote:

Leishmaniasis I would say - no halo seen

Submitted on 13/08/2010 14:14
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Marcela Saeb Lima - MSLDermatopato (Mexico, City) Wrote:

Good morning, and totally agree with Richard Carr´s comment about the distinction between Leishmania and Histoplasma. Today I think is Leishmania! Great week of magnificent cases Phillip!

Submitted on 13/08/2010 13:51
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Richard Carr - Warwick (UK) Wrote:

Leishmaniasis (again!). I remember Sebastain Lucas used to say he could not tell Leish from Histoplasma capsulatum on H&E in 10% of cases (i.e. the case the day before yesterday). I guess we always need a fungal stain to rule out Histoplasma! You were kind enough to use photographs of a case of Histoplasma (P.973 of your third edition) that I saw when visiting Malawi, Africa. That case had lots of histiocytes (as opposed to macrophages) mixed with plasma cells and lymphocytes but the picture in the book shows the beutiful capsule on the H&E as a distint halo, but I think I took that picture under oil emersion. Nice to relive the case and those wonderful times at St Thomas hospital!

Submitted on 13/08/2010 13:30
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Marwa Fawzi - Dermatology Department, Faculty of Medicine, Cairo University (Egypt) Wrote:

Leishmaniasis.

Submitted on 13/08/2010 13:20
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Phillip McKee - Overseas consultations (USA) Wrote:

Good morning all. It is useful to compare today's case with yesterday's. I will wait with interest to see what other people have to say.

Submitted on 13/08/2010 13:18
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Graham Reilly - Princess Elizabeth Hospital (Guernsey) Wrote:

Leishmaniasis.Plasma cells lymphocytes and macrophages with inclusions - good to see after the Histoplasmosis for comparison -if I`m right!

Submitted on 13/08/2010 10:35
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Mona Abdel-Halim - Dermatology Department, Faculty of Medicine, Cairo University (Egypt) Wrote:

Dear Sir, like you have commented and taught us in case 45, there is dense infiltrate of lymphocytes and plasma cells together with parasitized macrophages. Today this must be Leishmaniasis!! Thank u Sir.

Submitted on 13/08/2010 01:25
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Eman El-Nabarawy - Cairo University (Egypt) Wrote:

Leishmaniasis.

Submitted on 13/08/2010 00:51
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