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In this section we have spot diagnoses posted on a daily basis since June 2010, now over 4000! You can review the archived cases and read the suggested diagnoses by users and the final comment by the contributors.
Case are uploaded each week day by 10 am UK time with the correct diagnosis will generally be posted at 8 pm UK time. Why not view the most recent spot diagnosis and proffer a diagnosis?

Case Number : Case 17 Posted By: Guest

Please read the clinical history and view the images by clicking on them before you proffer your diagnosis.
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Gout
picture-1
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Go to records July 2010

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Admin_Dermpath

Admin_Dermpath 1,217

Posted

Phillip McKee - Overseas consultations () Wrote:

The diagnosis is Gout which appears as amorphous material in the dermis with an associated granulomatous reaction. The needle shaped crystals dissolve out in formalin fixed tissue and so fixation in alcohol is required for the preservation of sodium urate monohydrate deposits. Well done to Mo for remembering the earlier spot diagnosis (Case #4); as you say clinical history is important and in this case it occurred at a classical site and showed negative birefringence. Cutaneous oxalosis in comparison show striking yellow or blue birefringence when examined under polarised light. Thank you all for your contributions today. Have a good weekend and I will add cases next week.

Submitted on 02/07/2010 21:17
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Wayne Grayson - (Johannesburg, South Africa) Wrote:

What a gorgeous image! I favour a diagnosis of gout (rather than oxalosis), especially if the specimen was fixed in alcohol.

Submitted on 02/07/2010 19:31
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David Mee - (USA) Wrote:

Oxalosis dd Gout

Submitted on 02/07/2010 18:27
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Mo - (India) Wrote:

This is nice case of Gout in contrast to your case in June of Oxalosis, I think although I compared images and could not make a confident differentiation on HE - so need more history please

Submitted on 02/07/2010 16:43
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Carlos L. - (Spain) Wrote:

Gout

Submitted on 02/07/2010 16:39
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Jonathan Shelton - UK () Wrote:

Gout

Submitted on 02/07/2010 16:06
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Marwa M.Fawzi - Dermatology Department, Faculty of Medicine, Cairo University (Egypt) Wrote:

Gout

Submitted on 02/07/2010 09:32
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Eman El-Nabarawy - (Egypt) Wrote:

Oxalosis.DDx gout.

Submitted on 02/07/2010 06:27
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Rodrigo Restrepo - UPB (Mdlln.Colombia) Wrote:

Gout

Submitted on 01/07/2010 22:56
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Mona Abdel-Halim - Dermatology Department, Faculty of Medicine, Cairo University (Egypt) Wrote:

This is wouderful picture of gouty tophi (Urate Crystals)

Submitted on 01/07/2010 22:38
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