Case Number : Case 27 Posted By: Guest

Phillip McKee - Overseas consultations (USA) Wrote:

Well done all of you. The diagnosis is ichthyosis vulgaris. This case was very kindly shared with me by Dieter Metze, University of Munster, Germany. Have a great weekend and see you all on Monday

Submitted on 16/07/2010 21:13
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CP - (UK) Wrote:

A fabulous image - very clear at this high power. The diagnosis is icthyosis.

Submitted on 16/07/2010 17:55
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Wayne Grayson - (Johannesburg, South Africa) Wrote:

Ichthyosis vulgaris

Submitted on 16/07/2010 16:28
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Juan Carlos Garces - Hospital Oncológico / Hospital Luis Vernaza (Guayaquil Ecuador) Wrote:

I am late today... I am agree with Icthyosis vulgaris

Submitted on 16/07/2010 15:54
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Phillip McKee - Overseas Consultations (USA) Wrote:

Good morning everyone. You are all doing very well. The patient was dark-skinned hence the melanin pigment. Many thanks for your kind comment Yvonne.

Submitted on 16/07/2010 15:24
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Rodrigo Restrepo - UPB (Mdlln/Col) Wrote:

Icthyosis vulgaris

Submitted on 16/07/2010 14:22
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Mona Abdel-Halim - Dermatology Department, Faculty of Medicine, Cairo University (Egypt) Wrote:

Compact hyperkeratosis and reduced to absent granular layer. Diagnosis: Ichthyosis Vulgaris

Submitted on 16/07/2010 13:37
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Yvonne Bury - (UK) Wrote:

Hyperkeratosis with hypogranulosis, underlying keratinocytes appear normal and not vacuolated, prominent pigementation and pigment granules in stratum corneum, no dermal inflammation, ichthyosis seems very likely, but should it not be associated with moderate hyperkeratosis (that's what the books say not that I have seen a case myself) and this seems rather marked in this field? (of course we are only seeing a small high power field) The pattern of keratinization is somehow reminiscent of trichilemmal, dense hyperkeratin and no granular layer, but would expect a rather undulating junction. There are also lines perpendicular to the epidermis, which together with the abrupt keratinization makes me think about nail histology, which I favour in the end. But I still cannot explain the pigment. This is an excellent website and I have learned a lot looking at all the spot diagnosis.

Submitted on 16/07/2010 13:18
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Marwa Fawzi - Dermatology Department,Faculty of Medicine, Cairo university. (Egypt) Wrote:

Icthyosis vulgaris

Submitted on 16/07/2010 11:48
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galal el enany - cairo university (cairo egypt) Wrote:

ichthyosis vulgaris

Submitted on 16/07/2010 10:48
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Eman El-Nabarawy - Dermatology Department,Faculty of Medicine, Cairo university. (Egypt) Wrote:

compact Hyperkeratosis,diminished granular cell layer.Ichthyosis vulgaris.

Submitted on 16/07/2010 09:44
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Rachel - (Manchester) Wrote:

A thickened layer of compact keratin, and diminished granular layer, so Icthyosis

Submitted on 16/07/2010 09:05
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M N Mahmood - Uof ALBERTA (Edmonton, alberta) Wrote:

Icthyosis vulgaris

Submitted on 16/07/2010 04:45
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Marcela Saeb Lima - MSLDermatopato (Mexico City) Wrote:

Icthyosis

Submitted on 16/07/2010 03:48
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