Case Number : Case 33 Posted By: Guest

Phillip McKee - Overseas consultations (USA) Wrote:

Late as usual!! The tumor cells showed focal staining with keratin and EMA. I don't know what other immunohistochemistry was performed. The final diagnosis was monophasic synovial sarcoma.

Submitted on 26/07/2010 21:56
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Wayne Grayson - (Johannesburg, South Africa) Wrote:

A haemangiopericytomatous pattern is clearly evident. A more definitive diagnosis is not possible without immunohistochemistry, as there is a broad differential diagnosis to consider. If I have to come up with a spot diagnosis though, I would favour a synovial sarcoma.

Submitted on 26/07/2010 16:46
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Phillip McKee - Overseas consultations (USA) Wrote:

Good morning all. Good suggestions. I will give you the immunohistochemistry later.

Submitted on 26/07/2010 15:09
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Saleem Taibjee - Warwick () Wrote:

I agree with others, haemangiopericytoma-pattern. I would slightly favour solitary fibrous tumour based on patternless cellular arrangement in this field. Saleem

Submitted on 26/07/2010 13:31
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Donald Parker - (USA) Wrote:

Difficult case - hemangiopericytoma is no longer a specific entity I would believe. Synovial sarcoma I would have expected more spindling of the cells. Note quite sure of diagnosis - requires immuno' - off to bed now!

Submitted on 26/07/2010 13:29
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Richard Carr - Warwick (UK) Wrote:

Haemangiopericytomatous pattern can be seen in solitary fibrous tumour, synovial sarcoma, mesenchymal chondrosarcoma, deep benign fibrous histiocytoma, glomangiopericytoma, haemangiopericytoma (latter rare and diagnosis of exclusion). Looks highly cellular in this field though uniform cytology, I was thinking possibly a synovial sarcoma but needs immuno panel.

Submitted on 26/07/2010 09:44
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Eman El-Nabarawy - Dermatology Department,Faculty of Medicine, Cairo university. (Egypt.) Wrote:

Tumor of eccrine or apocrine origin.Apocrine hidradenoma.Hidroacanthoma simplex.Possible malignant change?

Submitted on 26/07/2010 06:50
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Mona Abdel-Halim - Dermatology Department, Faculty of Medicine, Cairo University (Egypt) Wrote:

With the central ramifyig endothelium lined ramifying vessel and the surrounding tightly packed cells, I am thinking of hemangiopericytoma. Solitary fibrous tumor may show areas of hemangiopericytoid pattern so it could be a differential.

Submitted on 26/07/2010 06:30
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Miah S. - (UK) Wrote:

Atypical basaloid cells with possible ductal structures ? porocarcinoma.

Submitted on 26/07/2010 00:34
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Juan Carlos Garcés - Hospital Oncológico / Hospital Luis Vernaza (Guayaquil Ecuador) Wrote:

"Hemangiopericytoid pattern": solitary fibrous tumor, synovial sarcoma, malignant peripheral nerve sheat tumor... Immunos: CD34, S100, EMA..

Submitted on 26/07/2010 00:27
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