Case Number : 106 Posted By: Guest

Phillip McKee - Overseas consultations (Sedona, Arizona, USA) Wrote:

Most of you have got the correct diagnosis. This is a high power view of folliculotropic mycosis fungoides. The lymphocytes are enlarged, hyperchromatic and have irregular contours. There is follicular interface change and infitration of the follicle by the atypical lymphocytes. Clinically, the patient had folliculocentric lesions in addition to plaques. I agree that clinicopathological correlation is critical. Differential diagnoses include pseudolymphomatous folliculitis, follicular lymphomatoid papulosis and at a stretch lichen planopilaris although lymphocyte atypia would not be seen in the last condition. I suppose that a lymphomatoid drug reaction could also be considered. It is important to remember that syringotropic lesions may also be seen in this variant of myosis fungoides. Many thanks for your kind comments Miah and Rich. I aim to please!! Another comment, I think that there others who view these cases but do not post a comment. If you look at the cases, please always leave a comment. You may well be correct and in any event, we are all continuously learning from one another. Phillip

Submitted on 04/11/2010 18:55
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Marwa Fawzi - Dermatology Department, Faculty of Medicine, Cairo University (Egypt) Wrote:

Folliculotropic mycosis fungoides

Submitted on 04/11/2010 18:42
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Richard Carr - Warwick (UK) Wrote:

That is a simply stunning image. My first thought was follicular MF/CTCL but agree needs clinical correlation as always.

Submitted on 04/11/2010 17:40
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ANDREW DANCKWERTS - WITS UNIVERSITY, JOHANNESBURG (JOHANNESBURG, RSA) Wrote:

CUTANEOUS T-CELL LYMPHOMA. DIFFERENIAL DIAGNOSIS INCLUED THE FOLLOWING: (1). ADULT T-CELL LEUKEAMIA / LYMPHOMA; (2). CUTANEOUS ANAPLATIC LYMPHOMA; (3). ADNEXOTROPIC MYCOSIS FUNGOIDES; (4). PERIPHERAL T-CELL LYMPHOMA (LESS LIKELY).

Submitted on 04/11/2010 16:32
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Galal Elenany - cairo university (dermatology department) Wrote:

folliclotrpic CTCL

Submitted on 04/11/2010 15:55
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Miah Singh - (UK) Wrote:

Dear All, the cells are just not atypical enough for me - I think I prefer reactive over neoplastic. Again stunning images - thank you Dr McKee for a brilliant site.

Submitted on 04/11/2010 15:43
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Mo - Trainee (India) Wrote:

Lymphomatoid drug eruption

Submitted on 04/11/2010 15:27
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francisco morales r - hosp gral puebla (puebla mexico) Wrote:

Foliculitis linfomatosa

Submitted on 04/11/2010 15:12
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Juan Carlos Garcés - Hospital Oncológico / Hospital Luis Vernaza (Guayaquil Ecuador) Wrote:

Good morning.. agree with folliculotropic mycosis fungoides

Submitted on 04/11/2010 14:54
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Mona Abdel-Halim - Dermatology Department, Faculty of Medicine, Cairo University (Egypt) Wrote:

Folliculotropic mycosis fungoides

Submitted on 04/11/2010 14:35
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Marcela Saeb Lima - Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán (Mexico City) Wrote:

Folliculotropic cutaneous T cell lymphoma. Needs clinicopathological correlation and inmunohistochemichal profile

Submitted on 04/11/2010 14:26
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Eman El-Nabarawy - Cairo University (Egypt) Wrote:

Folliculotropic MF.

Submitted on 04/11/2010 14:25
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Saleem Taibjee - Warwick () Wrote:

Let's throw folliculotropic MF into the mix of differentials!

Submitted on 04/11/2010 14:22
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Jonathan Shelton - (UK) Wrote:

I wondered about a pseudolymphomatous folliculitis

Submitted on 04/11/2010 14:10
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Donald Clarke - Trainee (UK) Wrote:

Interesting case which shows an interface dermatitis consistent with lupus or lichen planopilaris.

Submitted on 04/11/2010 13:38