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In this section we have spot diagnoses posted on a daily basis since June 2010, now over 4000! You can review the archived cases and read the suggested diagnoses by users and the final comment by the contributors.
Case are uploaded each week day by 10 am UK time with the correct diagnosis will generally be posted at 8 pm UK time. Why not view the most recent spot diagnosis and proffer a diagnosis?

Case Number : 109 Posted By: Guest

Please read the clinical history and view the images by clicking on them before you proffer your diagnosis.
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GVHD


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Admin_Dermpath

Posted

Phillip McKee - Overseas consultations (Sedona, Arizona, USA) Wrote:

Sorry for the problem with the comments. We will show this case tomorrow so that you can add comments. Phillip

Submitted on 10/11/2010 19:01
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Maria claudia - FEDERICO LLERAS (BOGOTÁ) Wrote:

MORPHEA

Submitted on 10/11/2010 00:09
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Phillip McKee - Overseas consultations (Sedona, Arizona, USA) Wrote:

Well done, all who spotted the melanin pigment. This represents incontinence and therefore indicates that there has beeen a prior episode of interface dermatitis. The scleredermiform background in the context of the melanin would make late GVHD the most likely diagnosis.

Submitted on 09/11/2010 18:39
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Eman El-Nabarawy - Cairo university (Egypt) Wrote:

Sclerodermoid GVHD (sclerodermoid changes with papillary dermal melanophages).

Submitted on 09/11/2010 14:47
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Donald Gates - (USA) Wrote:

Morphea vs sclerodermoid GVHD prefer the latter

Submitted on 09/11/2010 14:33
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Miah Singh - (Uk) Wrote:

I agree with Carlos and favour chronic GVHD as there seems to be dermal pigmentation

Submitted on 09/11/2010 13:21
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Rodrigo Restrepo - UPB/CES (Mdlln, Colombia) Wrote:

Chronic graft versus host disease with sclerodermatous changes

Submitted on 09/11/2010 13:02
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Marcela Saeb Lima - Instituto Nacional de Ciencia Médicas y Nutrición Salvador Zubirán (Mexico City) Wrote:

Morphea vs sclerodermoid GVHD, square punch biopsy....

Submitted on 09/11/2010 11:27
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Graham Reilly - Princess Elizabeth Hospital (Guernsey) Wrote:

Sclerosis of dermal collagen surrounding fat and sweat glands.Looks consistent with Morphoea

Submitted on 09/11/2010 11:06
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ANDREW DANCKWERTS - WITS UNIVERSITY, JHB (JHB, RSA) Wrote:

MORPHEA

Submitted on 09/11/2010 10:35
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Richard Carr - Warwick (UK) Wrote:

I would also mention sclerodermoid GVHD (in view of the "dyspigmentation")

Submitted on 09/11/2010 10:33
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Carlos B. - Consultant (Spain) Wrote:

Sclerodermoid condition - number of differentials including morphea, scleredema, PCT, radiation induced change, late GVHD - cannt think of anything else!

Submitted on 09/11/2010 10:31
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Marwa Fawzi - Dermatology Department, Faculty of Medicine, Cairo University (Egypt) Wrote:

Morphea

Submitted on 09/11/2010 08:30
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Mona Abdel-Halim - Dermatology Department, Faculty of Medicine, Cairo University (Egypt) Wrote:

Thickened homogenized collagen affecting the whole dermis and extending deeply in the subcutaneous tissue, I thought of Morphea Profunda.

Submitted on 09/11/2010 05:04
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