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In this section we have spot diagnoses posted on a daily basis since June 2010, now over 4000! You can review the archived cases and read the suggested diagnoses by users and the final comment by the contributors.
Case are uploaded each week day by 10 am UK time with the correct diagnosis will generally be posted at 8 pm UK time. Why not view the most recent spot diagnosis and proffer a diagnosis?

Case Number : Case 123 Posted By: Admin_Dermpath

Please read the clinical history and view the images by clicking on them before you proffer your diagnosis.
Submitted Date :
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Darier's Disease
picture-1
  Report Record
Go to records November 2010

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Admin_Dermpath

Admin_Dermpath 1,217

Posted

Phillip H McKee - Overseas consulations (Sedona, Arizona, USA) Wrote:

This is an interesting case. I am surprised that no-one has suggested pemphigus as a main diagnosis since the predominant feature is that of acantholysis. The differential diagnosis certainly includes Grover's disease and acantholytic acanthoma. Focal acantholytic dyskeratosis could also be considered although there are no corps ronds or grains of Darier. Elsewhere in this specimen (not shown) is a focus showing very typical Darier's disease and that was the clinical diagnosis.

Submitted on 29/11/2010 19:01
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Marwa Fawzi - Dermatology Department, Faculty of Medicine, Cairo University (Egypt) Wrote:

Grover's

Submitted on 29/11/2010 17:41
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Mona Abdel-Halim - Dermatology Department, Faculty of Medicine, Cairo University (Egypt) Wrote:

Thought of Grover's disease. However, being shared by Dr. Carr, I am afraid (as we have experienced before) a rare entity might be hidden in this section!!!!. Wish u all a nice week!!!!

Submitted on 29/11/2010 14:54
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Eman El-Nabarawy - Cairo University (Egypt) Wrote:

Grover's disease.

Submitted on 29/11/2010 14:12
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Donald Gates - (USA) Wrote:

Acntholytic disorder - nice pic

Submitted on 29/11/2010 14:10
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Miah Singh - (UK) Wrote:

Darier's or grover's

Submitted on 29/11/2010 13:27
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Carlos B - (Spain) Wrote:

Acantholysis - either Darier's, Grovers, or HH. Less likley pemphigus.

Submitted on 29/11/2010 13:26
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Marcela Saeb Lima - Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán (Mexico City) Wrote:

Focal acantholysis with dyskeratosis... clinicopathological correlation is needed

Submitted on 29/11/2010 13:16
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Juan Carlos Garcés - Hospital Oncológico / Hospital Luis Vernaza (Guayaquil, Ecuador) Wrote:

Good morning.. Incomplete acantholysis without dyskeratosis..Lymphcytic infiltrate with one eosinophil.. Grover's disease

Submitted on 29/11/2010 03:14
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Phillip H. McKee - Overseas consultations (Arizona, USA) Wrote:

The case was kindly shared with me by Dr Richard Carr, from the U.K.

Submitted on 29/11/2010 00:41
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