Case Number : case 94 Posted By: Guest

Iskander Chaudhry - Manchester Royal Infirmary (Manchester, UK) Wrote:

The final diagnosis is spindle cell lipoma. As Saleem Taibjee suggested there are no wreath-like giant cells. See you tomorrow.

Submitted on 19/10/2010 22:03
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Eman El-Nabarawy - Cairo University (Egypt) Wrote:

Spindle cells, vascular componant, plasma cells, Kaposi sarcoma???

Submitted on 19/10/2010 18:00
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Mona Abdel-Halim - Dermatology Department, Faculty of Medicine, Cairo University (Egypt) Wrote:

I think the two components are spindle cells and a vascular componet (multiple small capillary like vessels). If we will also consider the fat as a component of the tumor one would consider: Angiomyofibroblastoma of the vulva or cellular angiofibroma. If the fat in this section is irrelevant, one will consider angiofibroblastoma.

Submitted on 19/10/2010 17:55
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Sasi Attili - Ninewells University Hospital (Dundee, UK) Wrote:

A tough one for a junior like me but I shall dare to attempt a diagnosis anyway. I see a spindle cell tumour infiltrating into the fat lobules. Suspect these are fibroblasts. The fibroblasts infiltrating into the fat is atypical for a histiocytoma and I can't really see any myofibroblasts? Malignant fibrous histiocytoma crossed my mind but the cellular architecture does not look particularly text book typical. DFSP might be a possibility. However on the right hand side the vessel to me looks sick (I might be completely wrong) and there seems to be vessel wall necrosis with what looks like 'dust' surrounding. Therefore I am contemplating a vasculitis as well but can't really tie the two.

Submitted on 19/10/2010 17:11
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Saleem Taibjee - Warwick () Wrote:

The 2 components are: Spindle cell lipoma and Pleomorphic lipoma (hyperchromatic cells, although can't see the classical floret-like cells)

Submitted on 19/10/2010 17:08
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Iskander Chaudhry - Manchester Royal Infirmary (Manchester, UK) Wrote:

The tumour has two components and you are all focusing on just one!

Submitted on 19/10/2010 16:51
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Najla Ben-Ghashir - warrington Hospital (Uk) Wrote:

Thnk you Dr McKee for the great website. My DD would be fibrous hamartoma of infancy vs lipofibromatosis. The presence of whrly fibromyxoid area is in favour of the first option.

Submitted on 19/10/2010 16:26
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Eman El-Nabarawy - Cairo University (Egypt) Wrote:

Solitary Fibrous tumor, spindle cell lipoma, inflammatory pseudotumor.

Submitted on 19/10/2010 16:00
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francisco morales r - hospital general de puebla (puebla, méxico) Wrote:

Dermatofibrosarcoma

Submitted on 19/10/2010 14:09
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Marcela Saeb Lima - Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán (Mexico City) Wrote:

Plexiform fibrous histiocytoma

Submitted on 19/10/2010 13:05
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Mona Abdel-Halim - Dermatology Department, Faculty of Medicine, Cairo University (Egypt) Wrote:

Fibrocollagenous tissue, mature fat, some myxoid areas, thinking fibrous hamartoma of infancy!

Submitted on 19/10/2010 06:04
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