Case Number : case 99 Posted By: Guest

Phillip McKee - Overseas Consultations (Arizona) Wrote:

The diagnosis is glomus tumor. Knowing the site would have helped, in addition to the clinical history and seeing the entire lesion. I am sure once the diagnosis is given the characteristic features stick out. Saleem's judgement about the lack of ductal differentiation was spot on. See you tomorrow.

Submitted on 26/10/2010 23:21
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Mo - (India) Wrote:

Atypical poroma

Submitted on 26/10/2010 20:32
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Carlos B - (Spain) Wrote:

Looks atypical to me and wonder about an epithelioid haemangioendothelioma

Submitted on 26/10/2010 20:32
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Saleem Taibjee - Warwick () Wrote:

Wow, tough case, and perfect for making a fool of myself. I like the suggestions so far. The cells seem to be forming syncytial/cohesive sheets, and the morphology of the cells shows rather rounded cells with uniform nuclei showing fine chromatin, small nucleoli, and rather amphophilic cytoplasm. Some spaces between cells, but I wasn't 100% convinced of true lumina. I thought the cells look broadly lymphoplasmacytoid, so might add myoepithelial lesions such myoepithelioma into the mix, as well as include melanocytic and mastocytoma in the differential. Will be keen to see the answer on this one since really struggling here.

Submitted on 26/10/2010 17:18
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Marwa Fawzi - Dermatology Department, Faculty of Medicine, Cairo University (Egypt) Wrote:

Eccrine poroma

Submitted on 26/10/2010 16:48
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Eman El-Nabarawy - Cairo University (Egypt) Wrote:

Solid glomus tumor.

Submitted on 26/10/2010 15:08
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Mona Abdel-Halim - Dermatology Department, Faculty of Medicine, Cairo University (Egypt) Wrote:

Nice suggestions for a very difficult case to diagnose from this single image. I would like to add the possibility of a solid island of a metastatic carcinoid syndrome. Cells are uniform, small, some nuclei are hyperchromatic and pleomorphic. In one reported case, it mimicked primary adnexal poroid neoplasm, and glomus tumor is one of its DDx.

Submitted on 26/10/2010 14:00
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Marcela Saeb Lima - Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán (Mexico City) Wrote:

Agree with Dr. Danckwerts glomus tumor was my second diagnosis, but it might be the first.

Submitted on 26/10/2010 13:10
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ANDREW DANCKWERTS - WITS UNIVERSITY (JHB, RSA) Wrote:

SOLID GLOMUS TUMOUR - MONOMORPHIC ROUND CELLS WITH EOSINOPHILIC CYTOPLASM AND CENTRAL NUCLEI.

Submitted on 26/10/2010 12:32
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Marcela Saeb Lima - Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán (Mexico City) Wrote:

monotonous cells with round nuclei, small nucleoli with some ductule structures... it could be poroma

Submitted on 26/10/2010 12:13
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Marcela Saeb Lima - Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán (Mexico City) Wrote:

monotonous cells with round nuclei, small nucleoli with some ductule structures... it could be poroma

Submitted on 26/10/2010 12:13
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