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In this section we have spot diagnoses posted on a daily basis since June 2010, now over 4000! You can review the archived cases and read the suggested diagnoses by users and the final comment by the contributors.
Case are uploaded each week day by 10 am UK time with the correct diagnosis will generally be posted at 8 pm UK time. Why not view the most recent spot diagnosis and proffer a diagnosis?

Case Number : case 63 Posted By: Guest

Please read the clinical history and view the images by clicking on them before you proffer your diagnosis.
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epithelioid and spindled cell angiosarcoma


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Admin_Dermpath

Posted

Phillip McKee - Overseas consultations (Arizona, USA) Wrote:

Sorry I am late. It is always difficult to come to a final diagnosis on one single image. Your differential diagnoses were all appropriate. The actual diagnosis was a mixed epithelioid and spindled cell angiosarcoma with intracytoplasmic lumina. Elsewhere the tumor contained vascular lumina with pleomorphic endothelial cells, multilayering and mitotic activity.

Submitted on 06/09/2010 22:46
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Saleem Taibjee - Warwick () Wrote:

I favoured epithelioid haemangioendothelioma given the intracytoplasmic vacuolation in the context of a vascular lesion, but also wondered about KS with the suggestion of inclusions.

Submitted on 06/09/2010 17:50
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Doru Chirita - Military Hospital (Bucharest) Wrote:

Kaposi's Sarcoma

Submitted on 06/09/2010 16:28
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Lushen Pillay - Wits Dermatology, South Africa (South Africa) Wrote:

Unsure. Interesting pic. ? some sort of Haemangioma ??

Submitted on 06/09/2010 15:45
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Eman El-Nabarawy - Cairo university (Egypt) Wrote:

Epithelioid cells with intracytoplasmic vacules containing RBCs, eosinophils, lymphocytes. Could be Epithelioid hemangioma (angiolymphoid hyperplasia with eosinoplilia).

Submitted on 06/09/2010 14:20
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Mona Abdel-Halim - Dermatology Department, Faculty of Medicine, Cairo University (Egypt) Wrote:

This is a very difficult case. Vascular spaces,? Intracytoplasmic lumina, epithelioid like endothelial cells, extravasated RBCS. My DDX: epithelioid cutaneous angiomatous nodule, epithelioid hemangioendothelioma, epithelioid angiosarcoma. Less likely; bacillary epithelioid angiomatosis or pyogenic granuloma like Kaposi Sarcoma.

Submitted on 06/09/2010 14:16
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Marcela Saeb Lima - MSLDermatopato (Mexico City) Wrote:

Great week to everyone! Nice case for today, my diagnosis is Kaposi sarcoma

Submitted on 06/09/2010 10:08
________________________________________

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Admin_Dermpath

Posted

Phillip McKee - Overseas consultations (Arizona, USA) Wrote:

Sorry I am late. It is always difficult to come to a final diagnosis on one single image. Your differential diagnoses were all appropriate. The actual diagnosis was a mixed epithelioid and spindled cell angiosarcoma with intracytoplasmic lumina. Elsewhere the tumor contained vascular lumina with pleomorphic endothelial cells, multilayering and mitotic activity.

Submitted on 06/09/2010 22:46
________________________________________
Saleem Taibjee - Warwick () Wrote:

I favoured epithelioid haemangioendothelioma given the intracytoplasmic vacuolation in the context of a vascular lesion, but also wondered about KS with the suggestion of inclusions.

Submitted on 06/09/2010 17:50
________________________________________
Doru Chirita - Military Hospital (Bucharest) Wrote:

Kaposi's Sarcoma

Submitted on 06/09/2010 16:28
________________________________________
Lushen Pillay - Wits Dermatology, South Africa (South Africa) Wrote:

Unsure. Interesting pic. ? some sort of Haemangioma ??

Submitted on 06/09/2010 15:45
________________________________________
Eman El-Nabarawy - Cairo university (Egypt) Wrote:

Epithelioid cells with intracytoplasmic vacules containing RBCs, eosinophils, lymphocytes. Could be Epithelioid hemangioma (angiolymphoid hyperplasia with eosinoplilia).

Submitted on 06/09/2010 14:20
________________________________________
Mona Abdel-Halim - Dermatology Department, Faculty of Medicine, Cairo University (Egypt) Wrote:

This is a very difficult case. Vascular spaces,? Intracytoplasmic lumina, epithelioid like endothelial cells, extravasated RBCS. My DDX: epithelioid cutaneous angiomatous nodule, epithelioid hemangioendothelioma, epithelioid angiosarcoma. Less likely; bacillary epithelioid angiomatosis or pyogenic granuloma like Kaposi Sarcoma.

Submitted on 06/09/2010 14:16
________________________________________
Marcela Saeb Lima - MSLDermatopato (Mexico City) Wrote:

Great week to everyone! Nice case for today, my diagnosis is Kaposi sarcoma

Submitted on 06/09/2010 10:08
________________________________________

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