Case Number : Case 64 Posted By: Guest

Phillip McKee - Overseas Consultations (Arizona, USA) Wrote:

Thank you Saleem and all other contributors. Whilst this is a case of Granuloma Annulare it is important to keep ones differentials open, particularly when a GA-like pattern is described in other conditions. Thank you all for your contributions and hope to hear from you tomorrow.

Submitted on 07/09/2010 23:38
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Saleem Taibjee - Warwick () Wrote:

Looks like most are favouring GA which seems reasonable. I particularly wondered about actinic (O'Brien's) granuloma and atypical facial necrobiosis (many consider these conditions overlap) given the prominence of multinucleate giant cells, the relatively unstriking necrobiosis (in my eyes), suggestion of elastophagocytosis +/- solar elastosis.

Submitted on 07/09/2010 16:48
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Phillip McKee - Overseas consultations (Arizona) Wrote:

Well, interesting thoughts! I would like to know what other differentials you have in mind ... answer later on!

Submitted on 07/09/2010 16:11
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Carlos B - (Spain) Wrote:

Necrobiotic granuloma; favour GA followed by NL.

Submitted on 07/09/2010 16:07
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Lushen Pillay - Wits Dermatology, South Africa (South Africa) Wrote:

Granuloma Annulare most likely.

Submitted on 07/09/2010 15:15
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Marcela Saeb Lima - MSLDermatopato (Mexico City) Wrote:

Granuloma annulare

Submitted on 07/09/2010 13:32
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Andrew Danckwerts - University of Witwatersrand (Wits) (Johannesburg, RSA) Wrote:

Necrobiotic lesion : favour granuloma annulare. Cannot exclude Mycobacterial infection, foriegn body giant reaction or fungal infection. Also few eosinophils, cannot exclude cutaneous schistosomiasis.

Submitted on 07/09/2010 09:12
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Amira Tawdy - Cairo University (Egypt) Wrote:

Granuloma annulare

Submitted on 07/09/2010 08:58
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Marwa Fawzi - Dermatology Department, Faculty of Medicine, Cairo University (Egypt) Wrote:

Granuloma annulare

Submitted on 07/09/2010 02:23
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Mona Abdel-Halim - Dermatology Department, Faculty of Medicine, Cairo University (Egypt) Wrote:

Necrobiosis (Collagenolysis) associated with mucin deposition and surrounded with lymphocytes, histiocytes and giant cells. Lymphocytes and histiocytes are also seen perivascularly and interstitially. Granuloma Annulare.

Submitted on 07/09/2010 01:24
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Eman El-Nabarawy - Cairo University (Egypt) Wrote:

Granuloma annulare.

Submitted on 07/09/2010 01:16
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Juan Carlos Garcés - Hospital Oncológico / Hospital Luis Vernaza (Guayaquil Ecuador) Wrote:

Good evening.. Necrobiotic granuloma: Granuloma annulare, Giant cell elastolytic granuloma..

Submitted on 07/09/2010 01:09
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