Case Number : Case 66 Posted By: Guest

Phillip McKee - Overseas consultations (Arizona, USA) Wrote:

As you all seem to be going in the direction of hidradenoma with goblet cell metaplasia I will agree with the diagnosis of hidradenoma with goblet cell metaplasia (I have to go to a meeting shortly). I am not sure about the apocrine nature of the tumor. Lond ago, histochemistry very convincingly showed an enzyme expression pattern which very clearly indicated eccrine differentiation in these tumors. There does seem to be a trend to change the name or histogenesis/differentiation of so many tumors. To my simple mind all of this is very spurious and of little interest and of no real value. The only important thing is (A) that you recognize that the tumor is of sweat gland origin, ( that you determine that it is benign and (C) that you don't mistake it for a metastatic clear cell tumor. Perhaps I am just very old fashioned!! Phillip

Submitted on 09/09/2010 18:10
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Lushen Pillay - Wits Dermatology, South Africa (South Africa) Wrote:

Apocrine Hidradenoma looks like a good bet. Thanks for interesting cases !

Submitted on 09/09/2010 14:01
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Marcela Saeb Lima - MSLDermatopato (Mexico City) Wrote:

Hidradenoma with mucinous syringometaplasia

Submitted on 09/09/2010 13:11
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Phillip McKee - Overseas consultations (Arizona, USA) Wrote:

Good morning all. You all seem to be enjoying this case.

Submitted on 09/09/2010 13:04
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ANDREW DANCKWERTS - WITS UNIVERSITY (JOHANNESBURG, RSA) Wrote:

APOCRINE HIDROADENOMA WITH MUCINOUS SYRINGOMETAPLASIA

Submitted on 09/09/2010 12:38
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Marwa Fawzi - Dermatology Department, Faculty of Medicine, Cairo University (Egypt) Wrote:

I agree apocrine hidradenoma with focal goblet cell metaplasia.Thank you Dr. Phillip it is an excellant teaching site.

Submitted on 09/09/2010 08:58
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Eman El-Nabarawy - Cairo University (Egypt) Wrote:

Apocrine hidradenoma (nodular hidradenoma, clear cell hidradenoma, previously eccrine hidradenoma) with mucinous syringometaplasia.

Submitted on 09/09/2010 07:42
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Mona Abdel-Halim - Dermatology Department, Faculty of Medicine, Cairo University (Egypt) Wrote:

This field represents a tumor with biphasic cellular features: one cell type is rounded with esinophilic cytoplasm and the other is fusiform with clear cytoplasm. I think this is apocrine hidradenoma. I think the strange structure in this field represents mucinous syringometaplasia or focal goblet cell metaplasia in an apocrine hidradenoma.

Submitted on 09/09/2010 01:03
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Juan Carlos Garcés - Hospital Oncológico / Hospital Luis Vernaza (Guayaquil Ecuador) Wrote:

Good evening......Mucinous syringometaplasia? .. Clear cell hidradenoma with mucinous syringometaplasia?

Submitted on 09/09/2010 01:00
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Phillip McKee - Overseas consultations (Arizona, USA) Wrote:

As you all seem to be going in the direction of hidradenoma with goblet cell metaplasia I will agree with the diagnosis of hidradenoma with goblet cell metaplasia (I have to go to a meeting shortly). I am not sure about the apocrine nature of the tumor. Lond ago, histochemistry very convincingly showed an enzyme expression pattern which very clearly indicated eccrine differentiation in these tumors. There does seem to be a trend to change the name or histogenesis/differentiation of so many tumors. To my simple mind all of this is very spurious and of little interest and of no real value. The only important thing is (A) that you recognize that the tumor is of sweat gland origin, ( that you determine that it is benign and (C) that you don't mistake it for a metastatic clear cell tumor. Perhaps I am just very old fashioned!! Phillip

Submitted on 09/09/2010 18:10
________________________________________
Lushen Pillay - Wits Dermatology, South Africa (South Africa) Wrote:

Apocrine Hidradenoma looks like a good bet. Thanks for interesting cases !

Submitted on 09/09/2010 14:01
________________________________________
Marcela Saeb Lima - MSLDermatopato (Mexico City) Wrote:

Hidradenoma with mucinous syringometaplasia

Submitted on 09/09/2010 13:11
________________________________________
Phillip McKee - Overseas consultations (Arizona, USA) Wrote:

Good morning all. You all seem to be enjoying this case.

Submitted on 09/09/2010 13:04
________________________________________
ANDREW DANCKWERTS - WITS UNIVERSITY (JOHANNESBURG, RSA) Wrote:

APOCRINE HIDROADENOMA WITH MUCINOUS SYRINGOMETAPLASIA

Submitted on 09/09/2010 12:38
________________________________________
Marwa Fawzi - Dermatology Department, Faculty of Medicine, Cairo University (Egypt) Wrote:

I agree apocrine hidradenoma with focal goblet cell metaplasia.Thank you Dr. Phillip it is an excellant teaching site.

Submitted on 09/09/2010 08:58
________________________________________
Eman El-Nabarawy - Cairo University (Egypt) Wrote:

Apocrine hidradenoma (nodular hidradenoma, clear cell hidradenoma, previously eccrine hidradenoma) with mucinous syringometaplasia.

Submitted on 09/09/2010 07:42
________________________________________
Mona Abdel-Halim - Dermatology Department, Faculty of Medicine, Cairo University (Egypt) Wrote:

This field represents a tumor with biphasic cellular features: one cell type is rounded with esinophilic cytoplasm and the other is fusiform with clear cytoplasm. I think this is apocrine hidradenoma. I think the strange structure in this field represents mucinous syringometaplasia or focal goblet cell metaplasia in an apocrine hidradenoma.

Submitted on 09/09/2010 01:03
________________________________________
Juan Carlos Garcés - Hospital Oncológico / Hospital Luis Vernaza (Guayaquil Ecuador) Wrote:

Good evening......Mucinous syringometaplasia? .. Clear cell hidradenoma with mucinous syringometaplasia?

Submitted on 09/09/2010 01:00
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