Case Number : Case 72 Posted By: Guest

Phillip Mckee - Overseas consultations (Arizona, USA) Wrote:

Dear Mona, I will try to include more melanocytic lesions although it is difficult to illustrate them with just one spot diagnosis as often a constellation of features must be seen before rendering a final diagnosis. When the self assessment site comes on line, there will be plenty of melanocytic lesions for you to look at. PS Ss this is a dermatopathology site, I will not include salivary gland lesions which should make differential diagnosis a little easier.

Submitted on 18/09/2010 13:45
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Phillip McKee - Overseas Consultations (Arizona, USA) Wrote:

The diagnosis is lymphocyte-rich spiradenoma. I can understand why some couldn't see the wood (or forest, depending where you are from!) for the trees. But most of you were right. Well done and have a nice weekend and next spot will be out for Monday.

Submitted on 18/09/2010 13:10
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Rodrigo Restrepo - UPB (Mdlln/ Col) Wrote:

I agree J. Carlos. It is a lymphoepithelial lesion in salivary/lacrimalgland

Submitted on 17/09/2010 21:05
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Mona Abdel-Halim - Dermatology Department, Faculty of Medicine, Cairo University (Egypt) Wrote:

Dear Dr Phillip, I want to ask you for a favour. Is it possible to show us as frequent as you can melanocytic lesions, including dysplastic nevi, melanomas and rare forms of nevi as we seldom see them in Egypt and it will be a great opportunity to c such cases in your nice website with the very high qualities of the pictures. Thank u very much.

Submitted on 17/09/2010 18:23
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Wayne Grayson - (Johannesburg, South Africa) Wrote:

Eccrine spiradenoma.

Submitted on 17/09/2010 15:25
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Juan Carlos Garcés - Hospital Oncológico / Hospital Luis Vernaza (Guayaquil Ecuador) Wrote:

Good morning.. difficult to me with only this field. It looks like Spiradenoma. But the smaller cells with hypercromatic nuclei sometimes seem to be small lymphocytes. Thinking as a general pathologist I would consider a lymphoepithelial lesion in salivary gland

Submitted on 17/09/2010 14:21
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Galal Elenany - cairo university (faculty of medicine) Wrote:

the tumour is deeply basoplilic because the nuclei are closely aggregated two types of cells are seen the first with small dark nuclei and the second with large pale nuclei. ECCRINE SPIRADENOMA

Submitted on 17/09/2010 10:56
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Marwa Fawzi - Dermatology Department, Faculty of Medicine, Cairo University (Egypt) Wrote:

I agree with spiradenoma with nice rosettes.

Submitted on 17/09/2010 10:52
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Marcela Saeb Lima - MSLDermatopato (Mexico City) Wrote:

There are numerous lymphocytes and some plasma cells adjacent to some ductal structures. One might think of spiradenoma, but I do not see the biphasic cell population. Another thought is lymphoepitelioma-like carcinoma.

Submitted on 17/09/2010 10:40
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V Mehta - Trainee (UK) Wrote:

Spiroadenoma

Submitted on 17/09/2010 09:58
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Mona Abdel-Halim - Dermatology Department, Faculty of Medicine, Cairo University (Egypt) Wrote:

I can see a tumor made up of 2 types of cells, one small basaloid with dark hyperchromatic nuclei and the other larger with paler nucleus. The larger cells are forming duct like structures. Some lymphocytes are also seen as well as some droplets of hyaline material. This is a Spiradenoma. In cylindroma, one usually see both types of cells but in a rather special arrangment with island formations having the small basaloid cells in the periphery and the larger cells in the centre.

Submitted on 17/09/2010 07:33
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Eman El-Nabarawy - Cairo University (Egypt) Wrote:

Eccrine spiradenoma.DD Cylindroma.

Submitted on 17/09/2010 07:22
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