Case Number : Case 125 Posted By: Guest

Phillip McKee - Overseas consultations (Sedona, Arizona, USA) Wrote:

This case was very kindly shared with me by Wayne Grayson from South Africa. When dealing with unusual infections always consider that there might be a second disease. Acanthamebiasis is correct. One can tell acanthamebiasis from amebiasis by the absence of engulfed erythrocytes in the former and also by immunohistochemical techniques. There is however also a CMV inclusion in the top right corner of the field.

Submitted on 01/12/2010 19:50
___________________________________________________
Eman El-Nabarawy - Cairo University (Egypt) Wrote:

Agree with Dr Carlos, trophozoites of acanthameba.

Submitted on 01/12/2010 11:49
___________________________________________________
Mona Abdel-Halim - Dermatology Department, Faculty of Medicine, Cairo University (Egypt) Wrote:

As usual, brilliant idea Dr Carlos. I think I was half asleep yesterday!! I have misinterpreted lots of things!! Definitly there are trophozoites. I am not sure about the rounded structures with white halo, look slightly similar to the cyst form of acanthameba in some photos that I have looked up in the net. I agree with amebiasis, could be acanthamebiasis. Will never make a midnight diagnosis!!!

Submitted on 01/12/2010 05:10
___________________________________________________
Juan Carlos Garcés - Hospital Oncológico / Hospital Luis Vernaza (Guayaquil Ecuador) Wrote:

Good morning...Amebiasis.. probably Acanthamoeba...

Submitted on 01/12/2010 01:01
___________________________________________________
Mona Abdel-Halim - Dermatology Department, Faculty of Medicine, Cairo University (Egypt) Wrote:

I think I am looking to a mixture of hematopoeitic cells and their precursors. Extramedullary Hematopoeisis. May be a blueberry muffin lesion in a neonate or lesions from an adult with myelofibrosis.

Submitted on 30/11/2010 21:59
___________________________________________________