Case Number : Case 135 Posted By: Guest

Nagla Ramadan - Zagazig University (Egypt) Wrote:

Trichoepithelioma

Submitted on 15/12/2010 19:33
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Phillip McKee - Overseas consultations (Sedona, Arizona, USA) Wrote:

Trichoepithelioma it is. Many thanks Richard for your helpful comments regarding basaloid follicular hamartoma which I agree is indeed a confusing entity. I will put a nice example of one into the spot diagnosis one of these days.

Submitted on 15/12/2010 18:46
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Marcela Saeb Lima - Instituto Nacional de Ciencia Médicas y Nutrición Salvador Zubirán (Mexico City) Wrote:

Tricoepithelioma

Submitted on 15/12/2010 17:37
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Wayne Grayson - (Johannesburg, South Africa) Wrote:

Trichoepithelioma

Submitted on 15/12/2010 16:34
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Juan Carlos Garcés - Hospital Oncológico / Hospital Luis Vernaza (Guayaquil Ecuador) Wrote:

Good morning.. Trichoepithelioma. The section is quite tangencial so I think the connetion you see there is to the follicular epithelium...

Submitted on 15/12/2010 13:17
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Naglaa Nabil El Mongy - Cairo university (Egypt) Wrote:

Trich-epithelioma.

Submitted on 15/12/2010 12:42
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Richard Carr - Warwick (UK) Wrote:

I was a bit stupid suggesting the correct diagnosis on yesterday's case and dismissing it (I only had one case - actually images of a case Alex Lazar presented in London - in my collected files and the cells were much more plump/epithelioid). I am just reviewing all the literature on BFH and it is highly confusing and I am sure that not all the lesions put under this heading are the same. For example some authors say you do not get papillary mesenchymal cells in BFH and I think that should be more generally agreed on as a criterion to rule out BFH. Other authors described papillary mesenchymal cells and illustrated lesions that for me were more like trichoepithelioma as here. Trichoepitheliomas usually don't attach to the epidermis but if all the other features fit then I would not worry about that. More often we see trichoepithelioma like BCC and I find that immunos can helpful CD10 stains the papillary mesenchymal celsl in TE i.e. stromal predominante staining; while CD10 stains the basaloid epithelium (often peripherally) i.e. epithelial predominant staining in BCC. Merkel cells are absent or very sparse in BCC (very rare cases with numerous MCs) and numerous in about 50% of TEs/Trichoblastomas. All the other immunos listed in the literature seem less useful in our experience. Regards to all. Richard.

Submitted on 15/12/2010 09:35
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Amira Tawdy - Cairo University (Egypt) Wrote:

I suggest more basoloid follicular hamartoma

Submitted on 15/12/2010 08:10
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ANDREW DANCKWERTS - WITS UNIVERSITY, JOHANNESBURG (JOHANNESBURG, RSA) Wrote:

TRICHOEPITHELIOMA. DDx: KERATOTIC BASAL CELL CARCINOMA

Submitted on 15/12/2010 06:31
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Eman El-Nabarawy - Cairo University (Egypt) Wrote:

Trichoepithelioma. Cant exclude basaloid follicular hamartoma.

Submitted on 15/12/2010 05:32
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Mona Abdel-Halim - Dermatology Department, Faculty of Medicine, Cairo University (Egypt) Wrote:

Trichoepithelioma, focal epidermal connection is seen in trichoepithelioma.

Submitted on 15/12/2010 05:01
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Donald Trump - (USA) Wrote:

Tricho-epithelioma - only thing against this is the epidermal connection

Submitted on 14/12/2010 23:26
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