Case Number : Case 314 Posted By: Guest

Iskander Chaudhry - Central Manchester NHS Trust (Manchester UK) Wrote:

Well done the diagnosis is Epithelioid hemangioendothelioma - CD31 +++

Submitted on 25/08/2011 11:39
________________________________________
jose mari arrinda yeregui - hospital del bidasoa (hondarribia guipuzcoa SPAIN) Wrote:

HEMANGIOENDOTELIOMA EPITELIOID, VS EPITHELIOID SARCOMA IHQ ? Vim, AE! AE•3, cd 34, FVIII,

Submitted on 24/08/2011 16:14
________________________________________
jose mari arrinda yeregui - hospital del bidasoa (hondarribia guipuzcoa SPAIN) Wrote:

HEMANGIOENDOTELIOMA EPITELIOID, VS EPITHELIOID SARCOMA IHQ ? Vim, AE! AE•3, cd 34, FVIII,

Submitted on 24/08/2011 16:13
________________________________________
Rodrigo Restrepo - UPB/CES (Mdlln/Col) Wrote:

Cutaneous epithelioid angiomatous nodule

Submitted on 23/08/2011 22:50
________________________________________
Marie MD - () Wrote:

cutaneous epithelioid angiomatous nodule (CEAN)

Submitted on 23/08/2011 12:06
________________________________________
Eman El-Nabarawy - Cairo University (Egypt) Wrote:

Epithelioid hemangioendothelioma.

Submitted on 23/08/2011 09:18
________________________________________
Pablo Ortega-Espinosa - "Isidro Ayora" Hospital (Loja-Ecuador) Wrote:

This is a very interesting and difficult case, I think it looks like an Epitelioid Angiosarcoma.

Submitted on 23/08/2011 08:53
________________________________________
Claire and Pooja - Northwick Park Hospital (London) Wrote:

An epithelioid tumour with focal vacuoles. The differential includes epitheioid haemagioendothelioma, proximal epithelioid sarcoma and, less likely, carcinoma (primary or metastatic). We would do the following immuno: AE1/AE3, INI1, CD34, p63, S100, Fli1

Submitted on 23/08/2011 08:28
________________________________________
Marcela Saeb Lima - Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán (Mexico City) Wrote:

Anaplastic or pleomorphic Kaposi Sarcoma

Submitted on 23/08/2011 08:08
________________________________________
Mona Abdel Halim - Dermatology Department, Faculty of medicine, Cairo University (Egypt) Wrote:

Dear Dr Iskandar, I have placed a question in yesterday's case if u can kindly explain it to me, I would be very appreciating..

Submitted on 23/08/2011 07:28
________________________________________
Mona Abdel Halim - Dermatology Department, Faculty of medicine, Cairo University (Egypt) Wrote:

An infiltrative tumor, composed of nests and cords of large epithelioid cells with abundant esinophilic cytoplsm, vesicular nuclei, prominent nucleoli, and some nuclear pleomorphism. Some cells appear to have intracytoplasmic lumina with RBC's (3rd image). I think there are few mitoses. Thought of epithelioid hemangioendothelioma. Clinically it may present as multiple papules or nodules..

Submitted on 23/08/2011 07:04
________________________________________
ANDREW DANCKWERTS - NHLS / WITS UNIVERSITY (JOHANNESBURG, RSA) Wrote:

HIGH GRADE MALIGNANT NEOPLASM WITH A PROMINENT SPINDLE CELL MORPHOLOGY. I FAVOUR A SPINDLE CELL CARCINOMA / SARCOMATOID CARCINOMA. HOWEVER, THERE IS AN EXTENSIVE DIFFERENTIAL WHICH REQUIRES CONSIDERATION: (1) POORLY DIFFERENTIATED SCCA; (2) MELANOMA; (3) EPITHELIOD LEIYOMYOSARCOMA; (4) PLEOMORPHIC KAPOSI'S SARCOMA; (5) ATYPICAL FIBROBATOSIS; (6) METASTASIS. I WOULD LIKE TO PERFORM THE FOLLOWING IMMUNOHISTOCHEMICAL STAINS: CAM 5.2/AE1/3; S100/MITF/MELAN A/HMB45; SMA/MSA/DESMIN; HHV8/CD31; BETA CATENIN. CLINICO-PATHOLOGICAL CORRELATION IS ALSO REQUIRED.

Submitted on 23/08/2011 04:49
________________________________________