Case Number : Case 391 Posted By: Guest

Phillip McKee - Overseas Consultations (Cave Creek, Arizona, USA) Wrote:

Clinicopathological correlation is essential in this case. You all gave good differential diagnoses for interface but only one person mentioned LE and dismissed it! This is a case of florrid systemic lupus erythematosus.

Submitted on 08/12/2011 21:40
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Marwa Fawzy - Dermatology Department, Faculty of Medicine, Cairo University (Egypt) Wrote:

Pityriasis lichenoides

Submitted on 08/12/2011 21:09
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Eman El-Nabarawy - Cairo University (Egypt) Wrote:

Lichenoid drug reaction.

Submitted on 08/12/2011 20:39
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Mona Abdel Halim - Dermatology Dept, Cairo Univ. (Egypt) Wrote:

I think there is swollen endothelial cells and extravasated erythrocytes, as well as lymphocytes tightly cuffing some blood vessels, as well as a hint of parakeratosis, so I will consider first the possibility of PLC or a drug reaction,, Clinicopathological correlation is mandatory,,,

Submitted on 08/12/2011 19:26
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A Bansal - BCU HB (North Wales) Wrote:

? mycosis fungoides.

Submitted on 08/12/2011 19:11
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SCC - () Wrote:

Mycosis fungoides?

Submitted on 08/12/2011 18:18
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Diva Uribe Cordova - Hospital de Clínicas (La Paz) Wrote:

Drug reaction. Lichenoid interface, superficial perivascular lymphocytic infiltrate.

Submitted on 08/12/2011 17:38
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I. Abdul-kadir - SJUH (Leeds, UK) Wrote:

Erythema multiforme.

Submitted on 08/12/2011 17:15
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Marcela Saeb Lima - INCMNSZ (Mexico City) Wrote:

there is a interface dermatitis with epidermal atrophy in a background of solar elastosis... the differential is wide, but also consider poikilodermatous drug reaction, dermatomyositis, PLC maybe... obviously clinicopathological correlation is as Dr. Carr wrote... essential.

Submitted on 08/12/2011 16:23
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Sasi Attili - (UK) Wrote:

Lichenoid interface dermatitis with extravasated RBC associated with superficial perivascular lymphocytic infiltrate. Basket weave pattern uis still preserved so I am thinking of early EM. However there is the odd apoptotic keratinocyte and therefore drugs (? early FDE) and PLEVA in DD. Don't thinkfeatures atypical enough for CTCL, though Lichen aureus a possibility. Doesn't look like LE. Obviously need to correlate with clinical history...

Submitted on 08/12/2011 15:33
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Richard Carr - Warwick (UK) Wrote:

Is everyone sleeping or allergic to a rash! Interface/lichenoid reaction with red cell extravasation, slightly epidermotropic (targeting basal third) but no overt cytological atypia, parakeratotic scale. Differentials: Pityriasis lichenoides, lichen aureus, mycosis fungoides, drug reaction. Clinpath correlation is essential!

Submitted on 08/12/2011 15:08
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