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In this section we have spot diagnoses posted on a daily basis since June 2010, now over 4000! You can review the archived cases and read the suggested diagnoses by users and the final comment by the contributors.
Case are uploaded each week day by 10 am UK time with the correct diagnosis will generally be posted at 8 pm UK time. Why not view the most recent spot diagnosis and proffer a diagnosis?

Case Number : Case 394 Posted By: Guest

Please read the clinical history and view the images by clicking on them before you proffer your diagnosis.
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25 year old, nodules lower leg, clinically possible Kaposi’s sarcoma.


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Admin_Dermpath

Posted

Phillip McKee - Overseas Consultations (Cave Creek, Arizona, USA) Wrote:

This is quite a difficult case particularly if you had no clinical information. It comes from a patient with known HIV/AIDS. The top right picture is best as it shows the spindled cells permeating between the dermal collagen in addition to the infiltrate.

Submitted on 13/12/2011 22:38
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Mona Abdel Halim - Dermatology Department, Faculty of medicine, Cairo University (Egypt) Wrote:

To me this is very difficult,,There is a deep infiltrate surrounding the fat cells in the first image, with some changes that I am suspecting from this power to be fibrinoid changes in blood vessels????, could the collections of cells that r percieved as endothelial cells be granulomatous collections of histiocytes,,Could it be a granulomatous vasculitis???? Wegner's for example at a certain stage???

Submitted on 13/12/2011 20:43
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Pablo Ortega - (Loja-Ecuador) Wrote:

Agree with the clinical diagnosis

Submitted on 13/12/2011 19:04
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Sasi Attili - (UK) Wrote:

I am not quite sure about this one. There are extravasated RBC and a vascular proliferation of epithelioid looking cells with intracytoplasmic lumina, in a sclerotic stroma. I agree that this does look like a sclerotic Kaposi's. I have never heard of this variation but can't think of other differentials. Looking forward to the answer!

Submitted on 13/12/2011 17:53
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Marcela Saeb Lima - INCMNSZ (Mexico City) Wrote:

Kaposi sarcoma with sclerotic stroma

Submitted on 13/12/2011 17:25
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