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In this section we have spot diagnoses posted on a daily basis since June 2010, now over 4000! You can review the archived cases and read the suggested diagnoses by users and the final comment by the contributors.
Case are uploaded each week day by 10 am UK time with the correct diagnosis will generally be posted at 8 pm UK time. Why not view the most recent spot diagnosis and proffer a diagnosis?

Case Number : Case 279 Posted By: Guest

Please read the clinical history and view the images by clicking on them before you proffer your diagnosis.
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Female 42 years with hematuria and nodules on the scalp.


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Admin_Dermpath

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Phillip McKee - Overseas consultations (Arizona, USA) Wrote:

You are a very able bunch of dermatopathologists - the diagnosis is metastatic renal (clear cell) carcinoma

Submitted on 08/07/2011 04:21
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Marwa Fawzy - Dermatology Department, Faculty of Medicine, Cairo University (Egypt) Wrote:

Mestastatic carcinoma with clear cell change.

Submitted on 05/07/2011 13:23
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Marie MD - () Wrote:

Histo is compatible with metastatic RCC. Would want to know more to exclude mets of other clear cell tumors to skin/gu.

Submitted on 05/07/2011 11:08
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Juan Carlos Garcés - Hospital Oncológico / Hospital Luis Vernaza (Guayaquil Ecuador) Wrote:

Mestastatic renal cell carcinoma

Submitted on 05/07/2011 10:31
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Pablo Ortega - Hospital Isidro Ayora -Dermatopathology Department (Loja-Ecuador) Wrote:

a lot of necrosis, hemorrhage and clear cells with very atipical nuclei. With a history of hematuria, i will favor a metastatic renal cell carcinoma.

Submitted on 05/07/2011 08:59
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Rodrigo Restrepo - UPB/CES (Mdlln/Col) Wrote:

Metastatic renal carcinoma

Submitted on 05/07/2011 07:47
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Marcela Saeb Lima - Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán (Mexico City) Wrote:

metastatic renal cell carcinoma (clear cell)

Submitted on 05/07/2011 06:57
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Amira tawdy - Cairo University (Egypt) Wrote:

metastatic renal cell carcinoma since it goes as well with the clinical picture but I WANT to ask whether we can add as well seb carcinoma in the D.D OR not?

Submitted on 05/07/2011 06:10
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Eman El-Nabarawy - Cairo university (Egypt) Wrote:

Metastatic clear cell real cell carcinoma.

Submitted on 05/07/2011 05:58
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Reubina Wadee - NHLS/Wits University (Johannesburg, South Africa) Wrote:

Morphologically, the features are those of a clear cell neoplasm. The clinical history of haematuria would point toward a metastatic clear cell renal cell carcinoma. I would like to do immunohistochemical stains such as an AE1/3, Vimentin, Pax2 or Pax8, Renal cell carcinoma marker together with a CD10 to confirm.

Submitted on 05/07/2011 05:38
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Diana Alvarez - (The Netherlands) Wrote:

Metastatic clear cell renal carcinoma

Submitted on 05/07/2011 05:10
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ANDREW DANCKWERTS - NHLS, WITS UNIVERSITY (JOHANNESBURG, RSA) Wrote:

METASTATIC CLEAR CELL RENAL CARCINOMA. NEED IMMUNOHISTOCHEMISTRY TO CONFRIM: EMA / VIMENTIN / CD10. DIFFERNETIAL DIAGNOSIS INCLUDES: CLEAR CELL MELANOMA.

Submitted on 05/07/2011 04:55
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Hazem Hamed - Department of Histopathology, Imperial College London (LONDON) Wrote:

With the history of hematuria, This is a typical case of metastatic high grade renal cell carcinoma, clear cell type. CD10 is required to confirm.

Submitted on 05/07/2011 04:41
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Mona Abdel Halim - Dermatology Department, Faculty of medicine, Cairo University (Egypt) Wrote:

Metastatic Clear Cell Renal Cell Carcinoma

Submitted on 05/07/2011 04:35
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