Case Number : Case 286 Posted By: Guest

Richard Carr - Warwick (UK) Wrote:

Don't recognise this one sorry.

Submitted on 15/07/2011 03:11
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Phillip McKee - Overseas consultations (Cave Creek, Arizona, USA) Wrote:

Marginal zone lymphoma is the correct diagnosis. The immunohistochemistry was in keeping with this diagnosis although I cannot remember the exact details. This may have been a case of Richard Carr's. If it was, perhaps he can add some information. Well done everybody.

Submitted on 14/07/2011 11:43
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Diana Alvarez - (The Netherlands) Wrote:

Marginal zone lymphoma. Immunohistochemistry required.

Submitted on 14/07/2011 11:16
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James Carton - Imperial College (London) Wrote:

Very suggestive of marginal zone lymphoma but needs immuno to exclude a florid reactive lymphoid hyperplasia.

Submitted on 14/07/2011 09:37
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Eman El-Nabarawy - Cairo University (Egypt) Wrote:

Marginal Zone Lymphoma.

Submitted on 14/07/2011 09:28
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Marcela Saeb Lima - Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán (Mexico City) Wrote:

Marginal zone lymphoma

Submitted on 14/07/2011 09:25
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Juan Carlos Garcés - Hospital Oncológico / Hospital Luis Vernaza (Guayaquil Ecuador) Wrote:

Marginal zone lymphoma

Submitted on 14/07/2011 09:23
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Marwa Fawzi - Dermatology Department, Faculty of Medicine, Cairo University (Egypt) Wrote:

Marginal Zone Lymphoma.

Submitted on 14/07/2011 09:15
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Lucia Niño - U de Cartagena (Colombia) Wrote:

Atypical lymphoid proliferation, accompanied by plasma cells and Dutcher bodies The findings support small-cell lymphoma as first option marginal zone lymphoma, Immunohistochemistry is required to confirm the diagnosis CD20, CD5, CD23, cyclin D1, BCL6 and CD10

Submitted on 14/07/2011 09:10
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Rodrigo Restrepo - UPB/CES (Mdlln/Col) Wrote:

Marginal zone lymphoma

Submitted on 14/07/2011 08:42
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ANDREW DANCKWERTS - WITS UNIVERSITY, NHLS (JOHANNESBURG, RSA) Wrote:

THERE IS A DIFFUSE DYSCOHESIVE SHEET-LIKE PROLIFERATION OF CELLS, ADMIXED WITH PLASMA CELLS, HISTIOCYTES AND EOSINOPHILS. SOME OF THE LESIONAL CELLS HAVE A DISTINCT PLASMACYTOID MORPHOLOGICAL APPEARANCE. I FAVOUR A LOW GARDE HEAMATOLYMPHOID NEOPLASM, SUCH AS LYMPHOPLASMABLASTIC LYMPHOMA (LPL) OR MARGINAL ZONE LYMPHOMA (MZL). HOWEVER, A PLASMACYTOMA IS ALSO REQUIRES POSSIBLE CONSIDERATION. IMMUNOHISTOCHEMISTRY IS DEFINITIVE. NOTE: I THINK THE PATIENT IS A LITTLE YOUNG FOR BOTH LPL AND PLASMACYTOMA!!!

Submitted on 14/07/2011 08:17
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Hazem Hamed - Department of Histopathology, Imperial College London. (LONDON) Wrote:

A dense diffuse dermal polymorphic infiltrate composed of plasma cells, histiocytes and small to medium sized lymphoid cells with inconspicuous nucleoli with numerous small vascular proliferation. The features are of a low grade lymphoid neoplasm, suggestive of either lymphoplasmacytic lymphoma or marginal zone lymphoma. Immunohistochemistry is required to confirm.

Submitted on 14/07/2011 06:57
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Mona Abdel Halim - Dermatology Dept. Faculty of Medicine, Cairo University (Egypt) Wrote:

Marginal Zone Lymphoma.

Submitted on 14/07/2011 04:35
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