Case Number : Case 255 Posted By: Guest

Joel Rodríguez - (Tijuana) Wrote:

first diagnosis...Reticulohistiocytoma... multinucleated cell with eosinophilic and groundglass cytoplasm...and emperipolesis has been reported. 2nd consideration...Necrobiosis lipoidica.

Submitted on 01/06/2011 22:36
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Phillip McKee - Overseas Consultations (Arizona, US) Wrote:

This is difficult case of granulomatous inflammation and on this one image there are many differentials, however, the actual diagnosis was metastatic Crohn's disease. Better luck tomorrow.

Submitted on 01/06/2011 19:29
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Marwa Fawzi - Dermatology Department, Faculty of Medicine, Cairo University (Egypt) Wrote:

i will follow my first impression which goes with my dear Mona,granulomatous slack skin disease

Submitted on 01/06/2011 18:55
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Mona Abdel Halim - Dermatology Department, Faculty of medicine, Cairo University (Egypt) Wrote:

I think the lymphocytes have irregular contours (atypical). Together with the histiocytes, plasma cells, esinophils and MNGC showing emperipolesis, my first impression is granulomatous slack skin disease.

Submitted on 01/06/2011 11:05
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MSMD - (NY) Wrote:

Xanthogranuloma. The presence of plasma cells makes me think of necrobiotic xanthogranuloma

Submitted on 01/06/2011 10:44
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Eman El-Nabarawy - Cairo University (Egypt) Wrote:

Thought of Rosai Dorfman disease.

Submitted on 01/06/2011 08:27
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Maria Antonia Pastor - () Wrote:

I would add lupus vulgaris

Submitted on 01/06/2011 07:46
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Marcela Saeb Lima - Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán (Mexico City) Wrote:

The picture shows granulomas with multinucleated giant cells plasma cells and scattered eosinophils, there is a hint of emperipolesis.... I would think of cutaneous Rosai Dorfman vs lepra

Submitted on 01/06/2011 06:51
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