Case Number : Case 265 Posted By: Guest

Phillip McKee - Overseas consultations (Arizona, USA) Wrote:

The diagnosis is myofibroma. Better luck tomorrow.

Submitted on 16/06/2011 09:27
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Amira tawdy - Cairo University (Egypt) Wrote:

I go with fibrous hamartoma of infancy

Submitted on 15/06/2011 16:10
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Eman El-Nabarawy - Cairo University (Egypt) Wrote:

Infantile myofibromatosis.

Submitted on 15/06/2011 13:48
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Graham Reilly - Princess Elizabeth Hospital (Guernsey) Wrote:

A bit out of my depth here -but having looked at the books I would agree with Mona.Myofibroblasts,fibrous tissue and some myxoid stroma.Fibrous hamartoma of infancy.

Submitted on 15/06/2011 13:21
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Mona Abdel Halim - Dermatology dept. Cairo University (Egypt) Wrote:

This chapter of fibrous tissue tumors is really difficult. I did not c any hemangiopericytoma like branching vascular spaces found in majority of myofibromatosis. Also i could not percieve short fascicles of plump spindled myofibtoblasts with abundant esinophilic cytoplasm. This is why i did not think of it but i will not be surprised if i was wrong, because these fibrous tissue tumors are really irritating!!!!! Waiting to know the correct diagnosis accompanied by a detailed description from our great professor!

Submitted on 15/06/2011 13:12
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Pablo Ortega - Hospital Isidro Ayora -Dermatopathology Department (Loja-Ecuador) Wrote:

It looks like a mesenquimal tumor composed of fascicles of spindle cells with waxy nuclei (myofibroblasts), small areas of adipose tissue, and at higher magnification the mesenquimal cells are arranged in whorls. With these morphology and clinical features I also favor a Fibrous Hamartoma of Infancy.

Submitted on 15/06/2011 13:03
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Richard Carr - Warwick (UK) Wrote:

Not my strongest area but I will go for infantile myofibroma/myofibromatosis on the H&E

Submitted on 15/06/2011 12:25
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MSMD - () Wrote:

infantile myofibromatosis

Submitted on 15/06/2011 11:32
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Maria Antonia Pastor - () Wrote:

DFS protuberans?

Submitted on 15/06/2011 10:40
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Francisco Vilchez - Department of Dermatology. Virgen de la Victoria Clinical Universitary Hospital. (Málaga (Spain)) Wrote:

Agree, fibrous hamartoma of infancy

Submitted on 15/06/2011 07:54
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Mona Abdel Halim - Dermatology Department, Faculty of medicine, Cairo University (Egypt) Wrote:

Male, 1 year old, SC nodule, the scanning power shows adipose tissue, fibrous tissue and spindle cells. The spindle cells are highlighted in the second image, they have blunt ends and look like myofibroblasts, the 3rd image shows the fibrous tissue. I think the cells in the last image are kind of undifferentiated and the stroma is myxoid and contain few lymphocytes. I am thinking in Fibrous hamartoma of infancy.

Submitted on 15/06/2011 00:38
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