Case Number : Case 270 Posted By: Guest

Phillip McKee - Overseas consultations (Cave Creek, USA) Wrote:

Well done. You reached the correct diagnosis of low grade fibromyxoid sarcoma. Remember that on occasions this tumor can merge with hyalinizing spindle cell tumor with giant rosettes. This was a very difficult case.

Submitted on 22/06/2011 14:04
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MSMD - () Wrote:

low grade fibromyxoid sarcoma

Submitted on 22/06/2011 12:07
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Eman El-Nabarawy - Cairo University (Egypt) Wrote:

Low grade fibromyxoid sarcoma.

Submitted on 22/06/2011 10:06
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Mona Abdel Halim - Dermatology Department, Faculty of medicine, Cairo University (Egypt) Wrote:

Still examining the photos, the second image shows linear and whorly arrangement of the cells. Re-examining the 1st photo carefully can demonstrate multiple elongated vessels. I am now more convinced with the low grade fibromyxoid sarcoma. The first photo shows extensive myxoid areas. The age is typical (children and young adults).

Submitted on 22/06/2011 09:49
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Juan Carlos Garcés - Hospital Oncológico / Hospital Luis Vernaza (Guayaquil Ecuador) Wrote:

Good morning everybody... Low grade fibromyxoid sarcoma..

Submitted on 22/06/2011 09:40
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ANDREW DANCKWERTS - NHLS, WITS UNIVERSITY (JOHANNESBURG, RSA) Wrote:

PERIPHERAL NERVE SHEATH TUMOUR - I FAVOUR SCHWANNOMA (CELLULAR SUBTYPE). THIS LESION REQUIRES EXTENSIVE SAMPLING TO EXCLUDE TO PRESENCE OF MITOTIC FIGURES AND / OR NECROSIS TO EXCLUDE EVOLUTION TO A MALIGNANT PERIPHERAL NERVE SHEATH TUMOUR.

Submitted on 22/06/2011 07:43
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Mona Abdel Halim - Dermatology Department, Faculty of medicine, Cairo University (Egypt) Wrote:

Another DDX I would like to add is Low grade fibromyxoid sarcoma, it is also an encapsulated tumor with alternating cellular and myxoid areas. Vut I think it should be less cellular and shows many curvilinear vessels

Submitted on 22/06/2011 07:40
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Amira tawdy - Cairo University (Egypt) Wrote:

I like Mona idea being shwaannoma Can we add to the DD MALIGNANT PERIPHERAL NERVE SHEATH tumor, spindle cell variant

Submitted on 22/06/2011 06:26
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Mona Abdel Halim - Dermatology Department, Faculty of medicine, Cairo University (Egypt) Wrote:

Well circumsrcibed capsulated spindle cell neoplasm. It is clear that the neoplasm is made up of 2 areas, cellular areas with interlacing fascicles of spindle cells with intensly esinophilic cytoplasm, indistinct cell boundaries and spindled to cigar shaped nuclei. In many areas these cells appear to be arranged in rows. The other component of the tumor is a loose myxoid component in which the cells are separated by myxoid matrix. I will go for shwannoma and since the cellularity is high and there is no formation of classic verocay bodies and due to the presence of some storiform pattern I will consider cellular type of shwannoma.

Submitted on 22/06/2011 05:34
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