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In this section we have spot diagnoses posted on a daily basis since June 2010, now over 4000! You can review the archived cases and read the suggested diagnoses by users and the final comment by the contributors.
Case are uploaded each week day by 10 am UK time with the correct diagnosis will generally be posted at 8 pm UK time. Why not view the most recent spot diagnosis and proffer a diagnosis?

Case Number : Case 376 Posted By: Guest

Please read the clinical history and view the images by clicking on them before you proffer your diagnosis.
Submitted Date :
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Female 27 years, nodule on forearm.
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  Report Record
Go to records November 2011

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Admin_Dermpath

Admin_Dermpath 1,217

Posted

Phillip McKee - Overseas Consultations (Cave Creek, Arizona, USA) Wrote:

Well done everyone. Neurothekeoma is correct. NK1C3 is of help in the diagnosis of cellular neurothekeoma.

Submitted on 17/11/2011 13:47
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Sasi Attili - (UK) Wrote:

Isn't NKIC3 for Cellular Neurothekeoma's which are quite different?

Submitted on 17/11/2011 12:54
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A Bansal - BCU HB (North Wales) Wrote:

Agree, Neurothekeoma. Out of interest, would anyone use NK1C3 (CD57) to support this diagnosis?

Submitted on 17/11/2011 08:26
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Mona Abdel Halim - Dermatology Dept. (Egypt) Wrote:

Nerve sheath myxoma (neurothekoma)

Submitted on 17/11/2011 08:03
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Sasi Attili - (UK) Wrote:

Spindle cells in lobules of varying sizes set in myxoid stroma with lobules seperated by fibrous septae. Few bland multinucleate giant vells seen. Lobular architexture and circumscription= Neurothekeoma (Nerve sheath myxoma). DD- Superficial acral fibromyxoma (diffuse and not lobular, + wrong site). Similarly unlikely to be a myxoma. I believe myxoid variant of circumscribed and palisaded neuroma can look similar. However not sure if one can differentiate from a neurothekeoma as both are S100 +ve and an EMA +ve capsule might not be well formed in the former

Submitted on 17/11/2011 07:54
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Bostjan Luzar - Institute of Pathology, Medical Faculty University of Ljubljana (Ljubljana, Slovenia) Wrote:

Nerve sheeth myxoma

Submitted on 17/11/2011 06:35
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Marcela Saeb Lima - INCMNSZ (Mexico City) Wrote:

Neurothekeoma

Submitted on 17/11/2011 05:57
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Peter Karolyi - () Wrote:

Agree, Neurothekeoma.

Submitted on 17/11/2011 05:35
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Hazem Hamed - Department of Histopathology (London) Wrote:

Neurothekeoma.

Submitted on 17/11/2011 05:05

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