Case Number : Case 383 Posted By: Guest

Phillip McKee - Overseas Consultations (Cave Creek, Arizona, USA) Wrote:

A difficult case. The tumor was diffusely CD34 positive and was diagnosed as an atrophic DFSP

Submitted on 28/11/2011 11:45
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Sasi Attili - (UK) Wrote:

Need immunos. I was thinking of the differentials DFSP, cd34+ve medallion like dermal dendrocyte tumour, cellular atypical neurofibroma and Desmoid fibromatosis (due to the pleomorphic stellate/ spindle cells in the HP field, but probably a bit too superficial for this entity).

Submitted on 28/11/2011 08:56
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Mona Abdel Halim - Dermatology Department, Faculty of medicine, Cairo University (Egypt) Wrote:

My first impression is perineurioma..

Submitted on 28/11/2011 08:45
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Juan Carlos Garcés - Hospital Oncológico / Hospital Luis Vernaza (Guayaquil Ecuador) Wrote:

Good morning.. Agree with sclerosing perineurioma

Submitted on 28/11/2011 08:11
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Richard Carr - Warwick (UK) Wrote:

I will add a differential of "Plaque-like CD34-positive dermal fibroma (medallion-like dermal dendocyte hamartoma)". I have only seen it presented in meetings but should be relatively superficial (this lesion looks pretty deep). Agree with suggestions of perienurioma and DFSP in the differential here.

Submitted on 28/11/2011 07:18
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Peter Karolyi - () Wrote:

S. perineurioma, of course

Submitted on 28/11/2011 07:15
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Peter karolyi - () Wrote:

Sclerosing perineutioma

Submitted on 28/11/2011 07:14
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A Bansal - BCU HB (North Wales) Wrote:

On second thoughts, agree with perineurioma. Would like to see immunos (EMA, S100 protein etc.)

Submitted on 28/11/2011 06:33
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Rodrigo Restrepo - UPB/CES (Mdll/Col) Wrote:

Soft tissue perineurioma

Submitted on 28/11/2011 06:17
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Bostjan Luzar - Institute of Pathology Medical Faculty University of Ljubljana (Ljubljana, Slovenia) Wrote:

Dermatofibrosarcoma protuberans

Submitted on 28/11/2011 06:06
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Hazem Hamed - Department of Histopathology, Imperial College (London) Wrote:

Benign spindle cell tumour for immunohistochemistry. My first thought is Perineurioma.

Submitted on 28/11/2011 05:56
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A Bansal - BCU HB (North Wales) Wrote:

May be I'm missing something but just looks like a scar (keloidal) to me.

Submitted on 28/11/2011 05:33