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In this section we have spot diagnoses posted on a daily basis since June 2010, now over 4000! You can review the archived cases and read the suggested diagnoses by users and the final comment by the contributors.
Case are uploaded each week day by 10 am UK time with the correct diagnosis will generally be posted at 8 pm UK time. Why not view the most recent spot diagnosis and proffer a diagnosis?

Case Number : Case 343 Posted By: Guest

Please read the clinical history and view the images by clicking on them before you proffer your diagnosis.
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Male 80 years, multiple nodules on arm and neck.
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Go to records October 2011

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Admin_Dermpath

Admin_Dermpath 1,217

Posted

Phillip McKee - Overseas consultations (Cave Creek, USA) Wrote:

The differential diagnosis of small blue cell tumors is always difficult and depends upon previous history or immunohistochemistry. This case is a metastatic bronchial neuroendocrine tumor. Confirmed by both of the above. I will be away all of the rest of this week and Iskander will be looking afer the spot diagnoses

Submitted on 03/10/2011 14:06

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Eman El-Nabarawy - Cairo University (Egypt) Wrote:

Lymphoepithelioma like carcinoma.DD B-cell pseudolymphoma (I think I can see tingible body macrophages in the 2nd image).

Submitted on 03/10/2011 12:56

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Juan Carlos Garcés - Hospital Oncológico / Hospital Luis Vernaza (Guayaquil Ecuador) Wrote:

Lymphoepithelioma like carcinoma

Submitted on 03/10/2011 12:05

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Mona Abdel Halim - Dermatology Dept. Cairo University (Egypt) Wrote:

Dense nodular infiltrate composed of small lymphocytes with areas showing paler centres made up of large lymphocytes with vesicular nuclei. I think this could be chronic lymphocytic leukemia/ small lymphocytic lymphoma. The larger cells in the centres may be pro-lymphocytes or paraimmunoblasts. It might be also transforming to large BCL. Definitly extensive immunohistochemistry is needed.

Submitted on 03/10/2011 11:43

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Marcela Saeb Lima - INCMNSZ (Mexico City) Wrote:

large cell non Hodgkin lymphoma vs lymphoepithelioma like carcinoma

Submitted on 03/10/2011 07:51

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ANDREW DANCKWERTS - NHLS / WITS UNIVERSITY (JOHANNESBURG, RSA) Wrote:

HIGH GRADE MALIGNANT NEOPLASM. I FAVOUR A LARGE CELL HIGH GRADE NON HODGKIN LYMPHOMA. THE DIFFERENTIAL DIAGNOSIS INCLUDES: (1) AMELANOTIC MELANOMA; (2) POORLY DIFFERENTIATED METASTATIC CARCINOMA. I WOULD NEED IMMUNOHISTOCHEMICAL STAINS TO DIFFERENTIATE.

Submitted on 03/10/2011 05:28

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