Case Number : Case 475 Posted By: Guest

[b]Richard CArr - Warwick (UK) Wrote:[/b]

Thought I might regret my comments as there is clearly packeting on the low power and quite a naevus-like look to the cells as weel.

[size=2]Submitted on 04/04/2012 20:32[/size]
[b]Phillip McKee - Overseas Consultations (Cave Creek, Arizona, USA) Wrote:[/b]

I think that this is a classic cellular neurothekeoma. The packeting is best appreciated in the first low power image. Cutaneous myoepithelioma is extremely rare. In my experience it presents as a diffuse although circumscribed nodule lacking the packeting of cellular neurothekeoma. The infiltrate is somewhat polymorphous and there is stromal myxoid change and/or hyalinization. In any event, immunohistochemistry will resolve any diagnostic difficulty.

[size=2]Submitted on 04/04/2012 20:03[/size]
[b]Eman El-Nabarawy - Cairo university (Egypt) Wrote:[/b]

Cellular neurothecoma.

[size=2]Submitted on 04/04/2012 19:25[/size]
[b]Richard Carr - SWH (Warwick) Wrote:[/b]

Hmm. I really like the suggestion of myoepithelioma (annoyed I did not think of it myself!). Cellular neurothekeoma crossed my mind too although I think often more packeted neavus like with more sclerotic collagen. Myofibroma crossed my mind but more in desperation! I hope it is myoepithelioma. Many thanks for the supportive comments from colleagues on monday. Regards to all Richard

[size=2]Submitted on 04/04/2012 18:46[/size]
[b]Mona Abdel Halim - () Wrote:[/b]

Favoring cellular neurothekoma

[size=2]Submitted on 04/04/2012 18:21[/size]
[b]Marie MD - () Wrote:[/b]

DDX: Cellular neurothekeoma, plexiform histiocytic tumor (sans giant cells), and cutaneous myoepithelioma

[size=2]Submitted on 04/04/2012 17:51[/size]
[b]James Carton - Imperial College (London) Wrote:[/b]

I would also add in neurothekeoma and non-neural granular cell tumour to the differential.

[size=2]Submitted on 04/04/2012 15:53[/size]
[b]Yüksel Okumuş - Bursa State Hospital (Turkey) Wrote:[/b]

Cutaneous myoepithelioma.

[size=2]Submitted on 04/04/2012 12:24[/size]
[b]Izzat Abdul-kadir - ST2 - York Hospital (UK) Wrote:[/b]

I second myoepithelioma. It does not look dissimilar from a myoepithelioma I saw in a salivary gland.

[size=2]Submitted on 04/04/2012 12:04[/size]
[b]Engin Sezer - Acıbadem University () Wrote:[/b]

Round to oval cells with eosinophilic cytoplasm and stromal hyalinization reminiscence of cutaneous myoepithelioma.

[size=2]Submitted on 04/04/2012 11:35[/size]