Case Number : Case 492 Posted By: Guest

[b]SAMEH ABDELKODOUS - ALAZHAR UNIVERISTY (CAIRO) Wrote:[/b]

eosinophilic spongiosis. SORRY BUT I SEE THE BULLA INTRAEPIDERMAL AND NOT SUBEPIDERMAL SO MORE LIKLY PEMPHIGUS HERPITIFORM

[size=2]Submitted on 28/04/2012 11:03[/size]
[b]Richard Carr - Warwick (Stratford-Upon-Avon) Wrote:[/b]

Your are all spot on. The IMF was inconclusive in this case but histologically and clinically we favoured bullous pemphigoid. There was an excellent response to systemic steroids and the rash started to re-appear when the dose of prednisolone was reduced to 5mg. Based on clinicopathological correlation our diagnosis is bullous pemphigoid. It is important to remember that eosinophilic spongiosis is a reaction pattern and not a diagnosis. Remember IMF like nearly any other investigation is not 100% sensitive.

[size=2]Submitted on 28/04/2012 10:32[/size]
[b]Mahmood - UAH (Canada) Wrote:[/b]

BP

[size=2]Submitted on 28/04/2012 04:51[/size]
[b]Yüksel Okumuş - Bursa State Hospital (Turkey) Wrote:[/b]

Bulllous pemphigoid

[size=2]Submitted on 27/04/2012 19:31[/size]
[b]Marie MD - () Wrote:[/b]

BP

[size=2]Submitted on 27/04/2012 17:01[/size]
[b]Mona Abdel Halim - () Wrote:[/b]

BP

[size=2]Submitted on 27/04/2012 16:42[/size]
[b]Rodrigo Restrepo - UPB/CES (Mdlln/Col) Wrote:[/b]

Bulllous pemphigoid

[size=2]Submitted on 27/04/2012 16:29[/size]
[b]Eman El-Nabarawy - Cairo University (Egypt) Wrote:[/b]

BP for IF.

[size=2]Submitted on 27/04/2012 14:55[/size]
[b]Azza Mostafa - Ain Shams University (Cairo) Wrote:[/b]

Bullous pemphigoid

[size=2]Submitted on 27/04/2012 14:43[/size]
[b]Marwa Fawzy - Dermatology Department, Faculty of Medicine, Cairo University (Egypt) Wrote:[/b]

Bullous pemphigoid

[size=2]Submitted on 27/04/2012 14:13[/size]
[b]A Bansal - BCU HB (North Wales) Wrote:[/b]

Agree, likely bullous pemphigoid. Needs IF.

[size=2]Submitted on 27/04/2012 13:44[/size]
[b]Izzat Abdul-kadir - ST2 - York Hospital (UK) Wrote:[/b]

Bullous pemphigoid versus eosinophilic spongiosis.

[size=2]Submitted on 27/04/2012 13:37[/size]
[b]Marcela Saeb Lima - INCMNSZ (Mexico City) Wrote:[/b]

Bulllous pemphigoid

[size=2]Submitted on 27/04/2012 13:27[/size]
[b]Hazem Hamed - Department of Histopathology, Imperial College (LONDON) Wrote:[/b]

Subepidermal eosinophil rich bullous disease---Bullous pemphigoid. There is reepithelialization of the floor of the bulla in areas giving a false impression of being intraepidermal. IF is required to confirm Bullous pemphigoid.

[size=2]Submitted on 27/04/2012 13:27[/size]
[b]Engin Sezer - (Istanbul) Wrote:[/b]

Bullous pemphigoid. DIF is helpful to rule out LABD and PV.

[size=2]Submitted on 27/04/2012 13:10[/size]