Case Number : Case 493 Posted By: Guest

[b]Phillip H McKee - Overseas Consultations (Cave Creek, Arizona, United States) Wrote:[/b]

Spindle cell tumors are always difficult and require immunohistochemistry. However, Figure 4 does give a clue to the diagnosis owning to the perivascular accentuation. This is a malignant peripheral nerve sheath tumor. It emphasizes the fact that the typical herring bone pattern is often not a fibrosarcoma as your differential diagnoses show.

[size=2]Submitted on 30/04/2012 20:27[/size]
[b]Rodrigo Restrepo - UPB/CES (Mdlln/Col) Wrote:[/b]

Fibrosarcoma pattern

[size=2]Submitted on 30/04/2012 20:11[/size]
[b]Marie MD - () Wrote:[/b]

fibrosarcoma, monophasic synovial sarcoma...immunos needed

[size=2]Submitted on 30/04/2012 18:54[/size]
[b]Francisco Vílchez Márquez - Department of Dermatology. Clinical Universitary Hospital Virgen de la Victoria. (Málaga, Spain.) Wrote:[/b]

Leiomyosarcoma

[size=2]Submitted on 30/04/2012 18:21[/size]
[b]Eman El-Nabarawy - () Wrote:[/b]

Fibrosarcoma.

[size=2]Submitted on 30/04/2012 18:05[/size]
[b]Yüksel Okumuş - Bursa State Hospital (Turkey) Wrote:[/b]

Fibrosarcoma

[size=2]Submitted on 30/04/2012 18:03[/size]
[b]Mona Abdel Halim - () Wrote:[/b]

Fibrosarcoma pattern, immuno is required to verify other mentioned differentials

[size=2]Submitted on 30/04/2012 15:56[/size]
[b]A Bansal - BCU HB (North Wales) Wrote:[/b]

? Fibrosarcoma. DD: MPNST, synovial sarcoma (monophasic). Requires immunos.

[size=2]Submitted on 30/04/2012 15:43[/size]
[b]Marwa Fawzy - Dermatology Department, Faculty of Medicine, Cairo University (Egypt) Wrote:[/b]

Thought of low grade fibromyxoid sarcoma d.d DFSP ,leiomyosarcoma, monophasic synovial sarcoma and MPNST for immuno.

[size=2]Submitted on 30/04/2012 14:22[/size]
[b]Engin Sezer - (Istanbul) Wrote:[/b]

Malignant spindle cell proliferation with a herring-bone pattern. Fibrosarcomatous DFSP vs fibrosarcoma (which I favor the previous). CD34 and FISH including t(17;22) may be helpful.

[size=2]Submitted on 30/04/2012 13:44[/size]
[b]Izzat Abdul-kadir - ST2 - York Hospital (UK) Wrote:[/b]

Fibrosarcoma pattern. IHC to exclude leiomyosarcoma, monophasic synovial sarcoma and MPNST.

[size=2]Submitted on 30/04/2012 13:41[/size]