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In this section we have spot diagnoses posted on a daily basis since June 2010, now over 4000! You can review the archived cases and read the suggested diagnoses by users and the final comment by the contributors.
Case are uploaded each week day by 10 am UK time with the correct diagnosis will generally be posted at 8 pm UK time. Why not view the most recent spot diagnosis and proffer a diagnosis?

Case Number : Case 579 - 28 Aug Posted By: Guest

Please read the clinical history and view the images by clicking on them before you proffer your diagnosis.
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Female aged 28 years with widespread purpuric lesions clinically thought to represent polyarteritis nodosa or Wegener's granulomatosis.
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Go to records August 2012

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Guest
?Vascular occlusive disease, e.g. thrombotic thrombocytopaenic purpura.

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Guest Dr Engin Sezer

Guest Dr Engin Sezer

Posted

Intravascular thrombi with extravasated RBCs. Wide clinical range including TTP, ITP, cryoglobulinemia, antiphosholipid antibody syndrome, protein C-S deficiency, coumadin necrosis ext. Clinical and laboratory tests are required for CPC.

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Guest MarieMD

Guest MarieMD

Posted

Thrombotic vasculopathy. Broad DDx. Pt requires evaluation for:
Coagulation disorders (antiphospholipid syndrome, protein C/S def, Prothrombin gene mutation, Factor V Leiden, cryoglobulinemia, cryofibrinogenemia)...
Sneddon's syndrome, atrophie blanche, TTP, DIC, embolic events (bacterial endocarditis)
Drug reaction (Depo-Provera, IV cocaine)...

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Dr. Mona Abdel-Halim

Dr. Mona Abdel-Halim 508

Posted

Thrombotic vasculopathy (microvascular occlusion). Will think of all causes mentioned by Marie,,lovely images..

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Dr. Phillip McKee

Dr. Phillip McKee 130

Posted

I completely agree that this is a very difficult case and cannot be diagnosed without appropriate laboratory testing. It is in fact a rather beautiful example of the antiphospholipid syndrome.

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