Jump to content
In this section we have spot diagnoses posted on a daily basis since June 2010, now over 4000! You can review the archived cases and read the suggested diagnoses by users and the final comment by the contributors.
Case are uploaded each week day by 10 am UK time with the correct diagnosis will generally be posted at 8 pm UK time. Why not view the most recent spot diagnosis and proffer a diagnosis?

Case Number : Case 659 - 18 Dec Posted By: Guest

Please read the clinical history and view the images by clicking on them before you proffer your diagnosis.
Submitted Date :
   (0 reviews)
Male 67 years with a tumor at an unknown site.
picture-1
picture-2
picture-3
picture-4
  Report Record
Go to records December 2012

User Feedback


pekaragi
Extramammary Paget s disease- epidermotropic metastasis from a carcinoma of prostate

Share this comment

Link to comment
share_externally
Sasi Attili

Sasi Attili 85

Posted

Epidermotropic spread from underlying adenocarcinoma. Agreed that in a male prostratic Ca. has to be considered but need a wide immunopanel (CEA/ EMA to confirm, p63, CK 5, 7, 20, CDX2, PSA, TTF1, etc)

Share this comment

Link to comment
share_externally
Guest A Z
Extramammary Paget's diease, secondry to an adenocarcinoma. A panel of IHC and a relevant clinical history are essential for the diagnosis of the primary.

Share this comment

Link to comment
share_externally
Arif Usmani

Arif Usmani 17

Posted

Agree with A Z. Extramammary Paget’s vs Paget’s disease of male breast. Site, history and perhaps IHC are important in sorting this out.

Share this comment

Link to comment
share_externally
Guest Dr Engin Sezer

Guest Dr Engin Sezer

Posted

I feel that compression of basal keratinoyctes is diagnostic of (extra)mammary Paget with underlying dermal invasion of the tumour.. CK 7, 20 (sometimes indicating internal malignancy) and CEA may be very helpful.

Share this comment

Link to comment
share_externally
Dr. Mona Abdel-Halim

Dr. Mona Abdel-Halim 508

Posted

Epidermotropic metastatic adenocarcinoma.

Share this comment

Link to comment
share_externally
Guest Dr Engin Sezer

Guest Dr Engin Sezer

Posted

I now recognized that signet-ring cell appearance in fig 4 militates against the mammary version of Paget disease, thus making the extramammary form likely..

Share this comment

Link to comment
share_externally
Guest Bansal
[b]? Extramammary Paget's[/b]

Share this comment

Link to comment
share_externally
Iskander H. Chaudhry

Iskander H. Chaudhry 49

Posted

Thank you all for your comments and sorry for the delay in posting the final diagnosis, which in this case was apocrine carcinoma.

Share this comment

Link to comment
share_externally

×
×
  • Create New...