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In this section we have spot diagnoses posted on a daily basis since June 2010, now over 4000! You can review the archived cases and read the suggested diagnoses by users and the final comment by the contributors.
Case are uploaded each week day by 10 am UK time with the correct diagnosis will generally be posted at 8 pm UK time. Why not view the most recent spot diagnosis and proffer a diagnosis?

Case Number : Case 661 - 20 Dec Posted By: Guest

Please read the clinical history and view the images by clicking on them before you proffer your diagnosis.
Submitted Date :
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Female 42 years. Nodule on forearm.
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Go to records December 2012

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Guest Hazem Hamed

Guest Hazem Hamed

Posted

Clear cell hidradenoma. Stroma is not richly vascular to suggest metastatic clear cell RCC.

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Guest Bansal
Eccrine hidradenoma, clear cell variant.

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Guest Robledo F. Rocha

Guest Robledo F. Rocha

Posted

Metastatic clear cell carcinoma from the kidney.

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Guest Robledo F. Rocha

Guest Robledo F. Rocha

Posted

I don’t believe this lesion is clear cell hidradenoma because the tumor has a trabecular rather than a solid nodular pattern. Furthermore, there’s no cuboidal-lined ductal structures, but foci of necrosis are present in picture #1.

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Dr. Mona Abdel-Halim

Dr. Mona Abdel-Halim 508

Posted

Clear cell Hidradenoma..

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Arif Usmani

Arif Usmani 17

Posted

While metastatic RCC is an important and consequential differential diagnosis I favor clear cell hidradenoma pending IHCs. Metastatic renal cell carcinoma as per Lever’s histopathology of skin occurs almost always in men. There is no significant extravasation of red cells and nuclei are very bland. There also appears to be a transition from more basaloid cells in the periphery to clear cells in the center.

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Guest A Z
Agree with clear cell hiadradenoma.

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Sasi Attili

Sasi Attili 85

Posted

I worry when I see a clear cell hidradenoma which is a bit vascular and i can understand why colleagues have gone for RCC. However the age and the lack of vascular prominence, would be against the latter.

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Dr. Phillip McKee

Dr. Phillip McKee 130

Posted

Clear cell hidradenoma is correct. This is a classical example. Arif- Lever!! I think you need to buy a better book!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!
Remember as there are only 4 images so I don't always show all the features. There were plenty of ducts in the section. The absence of hemorrage and limited vascularity are against metastatic RCC as is the marked uniformity of the tumor cell nuclei.

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Arif Usmani

Arif Usmani 17

Posted

Dr. McKee you are right and its an old edition too. Do you have a suggestion?!!!!!

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