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In this section we have spot diagnoses posted on a daily basis since June 2010, now over 4000! You can review the archived cases and read the suggested diagnoses by users and the final comment by the contributors.
Case are uploaded each week day by 10 am UK time with the correct diagnosis will generally be posted at 8 pm UK time. Why not view the most recent spot diagnosis and proffer a diagnosis?

Case Number : Case 663 - 24 Dec Posted By: Guest

Please read the clinical history and view the images by clicking on them before you proffer your diagnosis.
Submitted Date :
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Female 72 years with multiple plaques, site unknown
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Go to records December 2012

User Feedback


Guest Hazem Hamed

Guest Hazem Hamed

Posted

Metastatic carcinoma with prominent epidermotropism mimicking paget's disease. I favor breast lobular carcinoma as a primary site. Immuno for CK7, CK20, TTF1, ER, GCDFP15, CEA, E-CADHERIN AND CD10 is required. DD includes metastatic signet ring carcinoma.

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Guest Bansal
Metastatic carcinoma. Needs wide immuno panel.

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Arif Usmani

Arif Usmani 17

Posted

Pagetoid metastatic carcinoma en cuirasse of the breast

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Dr. Mona Abdel-Halim

Dr. Mona Abdel-Halim 508

Posted

Epidermotropic metastatic carcinoma

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Guest Dr.Yüksel Okumuş

Guest Dr.Yüksel Okumuş

Posted

Epidermotropic metastatic mammary (lobular) carcinoma

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Guest Robledo F. Rocha

Guest Robledo F. Rocha

Posted

Agree with epidermotropic metastatic carcinoma. Although indian filing suggests lobular breast carcinoma, there is residual tubule formation and the neoplastic cells are too pleomorphic. So I think the primary tumor is ductal breast carcinoma.

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Dr. Phillip McKee

Dr. Phillip McKee 130

Posted

Well done. This is a metastasis with epidermotropism or Paget's disease if you like. I am not sure but agree that it certainly looks like breast would be a likely source for the primary. Have a wonderful Christmas. The spots will resume on December 26th.

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Guest
Wonderful Xmas for you all! Especially for you professor Dr. Phillip McKee

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Dr. Mona Abdel-Halim

Dr. Mona Abdel-Halim 508

Posted

Merry Christmas every body :-))

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