Case Number : Case 553 - 23 July Posted By: Guest

[b]Papillary eccrine adenoma arising in a background of organoid nevus. Though few inflammatory cells including occasional plasma cells are present the features are not typical of syringocystadenoma papilleferum. [/b]

Papillary projections, no decapitation, and typical location: agree, papillary eccrine adenoma.

Adenoma, be it eccrine or apocrine, tubular or papillary.

[i][b]Duct-like structures in the deeper layer [/b][/i]together with apocrine epithelial elements and plasma cells consistent with [b]syringocystadenoma papilliferum[/b].

nevus sebaceous with a tubular apocrine adenoma

Papillary eccrine adenoma

[b][font="Arial"][size="2"][color="#000080"]Tubulopapillary hidradenoma (PEA) arising in Nevus Sebaceous[/color][/size][/font][/b]

papillary ecrine adenoma in nevus sebaceous

Cystadenoma + papillary eccrine adenoma arising in an organoid nevus.

I favor tubular apocrine adenoma (tubulopapillary hidradenoma) on top of organoid nevus

[color=#231F20][b]Tubular apocrine adenoma[/b]. As with many adnexal tumours, [b]histopathological[/b] [b]overlap between tubular apocrine adenoma and papillary eccrine adenoma [/b]is not uncommon. Overlapping features with syringocystadenoma papilliferum are also seen, however, in classic [/color][color=#000000]syringocystadenoma[/color][color=#231F20] [/color][color=#000000]papilliferum, the inflammatory cells, particularly plasma cells, should be more[/color][color=#231F20] [/color][color=#000000]prominent. Apocrine cystadenomas have true papillae with a fibrous core.[/color]

I favored a diagnosis of tubular apocrine adenoma arising in an organoid nevus. Obviously I am well aware of the debate between apocrine or eccrine. It seems to me to be a rather futile exercise but being old fashioned, I restrict the term ecrrine tubular adenoma to those on the distal limbs. Although not very convincing, there is just a hint of aporcine secretion in the last image or perhaps it is just fanciful thinking.
On another matter, I have made two posts on my page of facebook today. I would really appreciate it if you could go to those comments and post your thoughts on either or both posts, preferably both. It would be very helpful to Iskander and myself and very much appreciated.