Case Number : Case 524 Posted By: Guest

[b]Phillip H McKee - Overseas Consultations (Cave Creek, Arizona, United States) Wrote:[/b]

Difficult case, hence the split in diagnoses. The correct diagnosis is urticaria pigmentosa. The lack of pagetoid spread would be against LCH. However special stains would confirm the correct diagnosis if there were any doubt.

[size=2]Submitted on 12/06/2012 17:52[/size]
[b]Juan Carlos Garcés - Hospital Oncológico / Hospital Luis Vernaza (Guayaquil Ecuador) Wrote:[/b]

Langerhans cell histiocytosis

[size=2]Submitted on 12/06/2012 14:41[/size]
[b]Rodrigo Restrepo - UPB/CES (Colombia) Wrote:[/b]

Langerhans cell histiocytosis

[size=2]Submitted on 12/06/2012 12:47[/size]
[b]A Bansal - BCU HB (North Wales) Wrote:[/b]

I think this is LCH with some cells showing a suggestion of longitudinal nuclear grooves. Confirm with immunos: CD1a, S100 protein and MCT.

[size=2]Submitted on 12/06/2012 12:37[/size]
[b]Zena Slim (SpR Histopath) - Wessex Deanery (QAH Portsmouth) Wrote:[/b]

Urticaria Pigmentosa. (not the right milieu of cells for LCH)

[size=2]Submitted on 12/06/2012 11:08[/size]
[b]Mona Abdel Halim - () Wrote:[/b]

I think yes it is Langerhans cell histiocytosis, some cells have reniform nuclei..

[size=2]Submitted on 12/06/2012 11:02[/size]
[b]Yüksel Okumuş - Bursa State Hospital (Turkey) Wrote:[/b]

Langerhans cell histiocytosis

[size=2]Submitted on 12/06/2012 10:52[/size]
[b]Pablo - Ortega (Loja, Ecuador) Wrote:[/b]

A lot of mast cells with sparse eos , Urticaria Pigmentosa

[size=2]Submitted on 12/06/2012 10:39[/size]
[b]Hazem Hamed - Imperial College (London) Wrote:[/b]

This is langerhans cell histiocytosis for CD1a, S100 and Langerin

[size=2]Submitted on 12/06/2012 10:22[/size]
[b]Francisco Vílchez-Márquez - Department of Dermatology. Ceuta Universitary Hospital. (Ceuta, Spain.) Wrote:[/b]

Mastocytosis (urticaria pigmentosa. Beautiful pictures!

[size=2]Submitted on 12/06/2012 10:16[/size]
[b]Mona Abdel Halim - () Wrote:[/b]

Urticaria pigmentosa

[size=2]Submitted on 12/06/2012 09:58[/size]
[b]Marcela Saeb Lima - INCMNSZ (Mexico City) Wrote:[/b]

urticaria pigmentosa

[size=2]Submitted on 12/06/2012 09:54[/size]