Case Number : Case 530 Posted By: Guest

[b]Phillip H McKee - Overseas Consultations (Cave Creek, Arizona, United States) Wrote:[/b]

I agree with the comments made after I posted the answer. The patient had a known bronchial tumor. I do not the immunohistochemistry results for this case.

[size=2]Submitted on 21/06/2012 17:40[/size] [b]Jaime A Mejia, MD - Medicina Diagnóstica (Cali, Colombia) Wrote:[/b]

I use to include the following DDx in epithelioid suspiciously metastatic lesions of this kind, in order: adenocarcinoma lung then gi, breast /prostate, mesothelioma, epithelioid angiosarcoma and melanoma. IHC: CK profile, CD31/CD34, p S-100. But as always nothing more useful than investigating clinical and imagenological clues.

[size=2]Submitted on 20/06/2012 19:53[/size] [b]Miguel Sanz - Hospital Principe de Asturias (Alcala de Henares, Madrid, Spain) Wrote:[/b]

I agree with Hazem Hamed and the stains showed here does not allow to exclude a mesothelioma. Mesothelioma can mimics adenocarcinoma and reach the skin covering the chest wall. I suppose that an histochemical pannel has been made in this case and the diagnosis of adenocarcinoma is based on the findings of the inmunophenotype profile.

[size=2]Submitted on 20/06/2012 18:06[/size] [b]Phillip H McKee - Overseas Consultations (Cave Creek, AZ, USA) Wrote:[/b]

I agree that it could represent part of a high grade hidradenocarcinoma or porocarcinoma but one must always exclude a metastasis (unless an origin is seen). The diagnosis is metastatic bronchial adenocarcinoma. The clinical information is helpful since the chest is the commonest site for a cutaneous metastsis with this tumor.

[size=2]Submitted on 20/06/2012 17:29[/size] [b]Reynaldo Falcón-Escobedo - School of Medicine, Autonomous University of San Luis Potosí (San Luis Potosí, México) Wrote:[/b]

I agree with the diagnosis of metastatic adenocarcinoma, but I would suggest the diagnosis of Porocarcinoma.

[size=2]Submitted on 20/06/2012 16:32[/size] [b]Marwa Fawzy - Dermatology Department, Faculty of Medicine, Cairo University (Egypt) Wrote:[/b]

Metastatic adenocarcinoma

[size=2]Submitted on 20/06/2012 15:22[/size] [b]Juan Carlos Garcés - Hospital Luis Vernaza /Hospital Oncológico (Guayaquil Ecuador) Wrote:[/b]

Poorly differntiated adenocarcinoma

[size=2]Submitted on 20/06/2012 14:36[/size] [b]Rodrigo Restrepo - UPB/CES (Mdlln/COL) Wrote:[/b]

Metastatic carcinoma

[size=2]Submitted on 20/06/2012 12:53[/size] [b]Yüksel Okumuş - Bursa State Hospital (Turkey) Wrote:[/b]

Metastatic carcinoma. Pulmonary Adenoca? GCC?

[size=2]Submitted on 20/06/2012 12:12[/size] [b]Marcela Saeb Lima - INCMNSZ (Mexico City) Wrote:[/b]

Metastatic adenoCa

[size=2]Submitted on 20/06/2012 11:05[/size] [b]I. Abdul-kadir - ST2 - York Hospital (UK) Wrote:[/b]

Adenocarcinoma. Porbably metastatic, but could it be eccrine carcinoma?

[size=2]Submitted on 20/06/2012 09:54[/size] [b]Hazem Hamed - Imperial College (London) Wrote:[/b]

Clinicoradiological correlation also is required to exclude metastasis before considering a primary neoplasm.

[size=2]Submitted on 20/06/2012 09:48[/size] [b]Hazem Hamed - Imperial College (London) Wrote:[/b]

Malignant poorly differentiated epithelioid neoplasm, most likely metastatic for immuno. DD includes: Mesothelioma, adenocarcinoma (from lung or elsewhere) and less likely non seminomatous germ cell tumour.

[size=2]Submitted on 20/06/2012 09:43[/size]