Case Number : Case 534 Posted By: Guest

[b]Phillip H McKee - Overseas Consultations (Cave Creek, AZ, United States) Wrote:[/b]

Although as with all dermal spindle cell lesions, immunohistochemistry is essential to make a diagnosis unless an epidermal origin or melanin etc is present. The diagnosis in this example is AFX.

[size=2]Submitted on 26/06/2012 16:56[/size]
[b]Juan Carlos Garcés - Hospital Luis Vernaza /Hospital Oncológico (Guayaquil Ecuador) Wrote:[/b]

AFX

[size=2]Submitted on 26/06/2012 14:01[/size]
[b]Engin Sezer - (Istanbul) Wrote:[/b]

DDx including pseudovascular SCC, AFX and angiosarcoma (favoring the first entity based on faintly basophilic material in the lumina on fig. 2).

[size=2]Submitted on 26/06/2012 12:57[/size]
[b]Rodrigo Restrepo - UPB/CES (Mdlln/Col) Wrote:[/b]

Atypical fibroxanthoma

[size=2]Submitted on 26/06/2012 12:52[/size]
[b]Marcela Saeb Lima - INCMNSZ (Mexico City) Wrote:[/b]

Angiosarcoma vs AFX vs SCC

[size=2]Submitted on 26/06/2012 12:15[/size]
[b]Yüksel Okumuº - Bursa State Hospital (Turkey) Wrote:[/b]

My first impression is AFX mimicking vascular lesion. DD: Angiosarcoma

[size=2]Submitted on 26/06/2012 11:58[/size]
[b]Francisco Vílchez-Márquez - Department of Dermatology. Ceuta Universitary Hospital. (Ceuta, Spain.) Wrote:[/b]

Angiosarcoma

[size=2]Submitted on 26/06/2012 11:43[/size]
[b]I. Abdul-kadir - ST2 - York Hospital (UK) Wrote:[/b]

Malignant spindle-cell neoplasm. Cytoplasmic vacuolation makes me think of endothelial differentiation, i.e. angiosarcoma.

[size=2]Submitted on 26/06/2012 10:30[/size]