Case Number : Case 461 Posted By: Guest

[b]Scott Sanders - Warwick Hospital (UK) Wrote:[/b]

The low power appearance is very naevus-like and the deep aspect of the lesion shows maturation with cells streaming off singly and in cords rather than an expansile growth pattern. The presence of a few mitoses is concerning but for me there would have to be significant mitotic activity including atypical mitoses to strongly favour naevoid melanoma over an 'active' naevus.

[size=2]Submitted on 19/03/2012 12:53[/size]
[b]Phillip McKee - Overseas Consultations (Cave Creek, Arizona, USA) Wrote:[/b]

Majority rules okay. Nevoid melanoma is correct. Clues to the diagnosis are subtle lack of maturation, mild pleomorphism, type-A cells at the top and bottom of the lesion, nucleolar prominence and mulitple mitoses (image 5)

[size=2]Submitted on 15/03/2012 19:26[/size]
[b]ANDREW DANCKWERTS - (JOHANNESBURG, RSA) Wrote:[/b]

NEVOID MELANOMA

[size=2]Submitted on 15/03/2012 17:43[/size]
[b]Diana Alvarez - () Wrote:[/b]

Nevoid melanoma.

[size=2]Submitted on 15/03/2012 16:39[/size]
[b]Pablo Ortega - Laboratorio de Patologia Ortega (Loja-Ecuador) Wrote:[/b]

Benign melanocytic nevus

[size=2]Submitted on 15/03/2012 15:30[/size]
[b]Izzat Abdul-kadir - ST2 - York Hospital (UK) Wrote:[/b]

There's symmetry, circumscription and maturation. However, there seems to be "atypia" and dermal mitoses, trumping the latter. Hence, naevoid melanoma.

[size=2]Submitted on 15/03/2012 15:25[/size]
[b]Engin Sezer - Acıbadem University (Istanbul, Turkey) Wrote:[/b]

Congenital melanocytic nevus showing a deep Indian-file pattern, uniform population of type A cells without tendency to form discrete nests superficially and pseudovascular spaces. Mitotic figures remind the motto 'nevi must live'.

[size=2]Submitted on 15/03/2012 14:43[/size]
[b]Rodrigo Restrepo - UPB/CES (Mdlln/Col) Wrote:[/b]

Nevoid Melanoma

[size=2]Submitted on 15/03/2012 14:32[/size]
[b]Yüksel Okumuş - Bursa State Hospital (Turkey) Wrote:[/b]

For differantial dignose nevoid melanoma with the others (mitotically active banal naevi, clonal naevus, congenital naevus etc.) I advise the link bellow. (McKEE's article) http://jcp.bmj.com/content/57/11/1121.full

[size=2]Submitted on 15/03/2012 14:01[/size]
[b]Mona Abdel Halim - () Wrote:[/b]

Nevoid melanoma

[size=2]Submitted on 15/03/2012 13:54[/size]
[b]Sasi Attili - (United Kingdom) Wrote:[/b]

It is certainly a naevoid lesion.This is a tough one for me to make a diagnosis based on 4 images. But, agree that naevoid melanoma is certainly a possibility

[size=2]Submitted on 15/03/2012 13:50[/size]
[b]Marcela Saeb Lima - INCMNSZ (Mexico City) Wrote:[/b]

Nevoid melanoma

[size=2]Submitted on 15/03/2012 13:45[/size]
[b]omar erdogan - () Wrote:[/b]

Mitotically active naevi or congenital nevi

[size=2]Submitted on 15/03/2012 13:42[/size]
[b]Yüksel Okumuş - Bursa State Hospital (Turkey) Wrote:[/b]

Nevoid Melanoma

[size=2]Submitted on 15/03/2012 13:26[/size]
[b]A Bansal - BCU HB (North Wales) Wrote:[/b]

Melanoma, naevoid variant.

[size=2]Submitted on 15/03/2012 13:03[/size]
[b]Wilber J. Martínez C. - CES University (Medellín COL) Wrote:[/b]

Nevoid melanoma

[size=2]Submitted on 15/03/2012 12:53[/size]