Case Number : Case 472 Posted By: Guest

[b]Phillip McKee - Overseas Consultations (Cave Creek, Arizona, USA) Wrote:[/b]

There was no sign of an origin from the surface epithelium and all the differential diagnoses were excluded with immunohistochemistry. Spindle cell AFX was the ultimate diagnosis. Please check yesterday's case for my comments.

[size=2]Submitted on 30/03/2012 18:10[/size]
[b]Francisco Vílchez Márquez - Department of Dermatology. Clinical Universitary Hospital Virgen de la Victoria (Málaga, Spain) Wrote:[/b]

I bet Leiomyosarcoma.

[size=2]Submitted on 30/03/2012 17:32[/size]
[b]Pablo Ortega - (Loja-Ecuador) Wrote:[/b]

spindle cell squamous carcinoma

[size=2]Submitted on 30/03/2012 16:52[/size]
[b]Graham Reilly - PEH (Guernsey) Wrote:[/b]

Spindle cell tumour - requires immunohistochem to differentiate between SCSCC, melanoma, leiomyosarcoma or AFX.

[size=2]Submitted on 30/03/2012 16:30[/size]
[b]Marwa Fawzy - Dermatology Department, Faculty of Medicine, Cairo University (Egypt) Wrote:[/b]

AFX

[size=2]Submitted on 30/03/2012 16:24[/size]
[b]Mona Abdel Hali - () Wrote:[/b]

My first impression is AFX

[size=2]Submitted on 30/03/2012 16:12[/size]
[b]Juan Carlos Garcés - Hospital Oncológico / Hospital Luis Vernaza (Guayaquil Ecuador) Wrote:[/b]

AFX

[size=2]Submitted on 30/03/2012 15:46[/size]
[b]Marcela Saeb Lima - INCMNSZ (Mexico City) Wrote:[/b]

AFX vs spindle SCC

[size=2]Submitted on 30/03/2012 14:28[/size]
[b]Rodrigo Restrepo - UPB/CES (Mdlln/Col) Wrote:[/b]

Spindle cell non pleomorphic AFX

[size=2]Submitted on 30/03/2012 13:04[/size]
[b]Eman El-Nabarawy - (Egypt) Wrote:[/b]

Dear Dr Hazem, I thought of PHAT also in case 470 but I think it lacks the telengeictatic vessels!! Thanks.

[size=2]Submitted on 30/03/2012 12:55[/size]
[b]Hazem Hamed - Department of Histopathology, Imperial College (London) Wrote:[/b]

Can you please revisit case 470? I thought of PHAT in the differntial diagnosis. Does anyone have any experience on this tumour? Thanks

[size=2]Submitted on 30/03/2012 12:32[/size]
[b]Amira Tawdy - Cairo University (Egypt) Wrote:[/b]

I think of trichelemmal carcinoma or AFX

[size=2]Submitted on 30/03/2012 12:16[/size]
[b]Izzat Abdul-kadir - ST2 - York Hospital (UK) Wrote:[/b]

I think without immunohistochemistry any diagnosis is a guess. The 5 possibilities, in no order, are: AFX, SCSCC, SCM, LMSC & SCA.

[size=2]Submitted on 30/03/2012 12:14[/size]
[b]Yüksel Okumuş - Bursa State Hospital (Turkey) Wrote:[/b]

Spindle cell atypical fibroxanthoma.

[size=2]Submitted on 30/03/2012 12:03[/size]
[b]Bostjan Luzar - Institute of Pathology, Medical Faculty University of Ljubljana (Ljubljana, Slovenia) Wrote:[/b]

Spindle cell non pleomorphic AFX. Originally reported by Calonje E et al. Histopathology 1993;22:247-54.

[size=2]Submitted on 30/03/2012 12:00[/size]
[b]Eman El-Nabarawy - (Egypt) Wrote:[/b]

Leiomyosarcoma.

[size=2]Submitted on 30/03/2012 11:53[/size]
[b]Hazem Hamed - Department of Histopathology, Imperial College (London) Wrote:[/b]

DD includes: Spindle cell melanoma, spindle cell squamous carcinoma, angiosarcoma, and AFX for immunohistochemistry.I think leiomysarcoma is less likely.

[size=2]Submitted on 30/03/2012 11:43[/size]