Case Number : Case 498 Posted By: Guest

[b]Richard Carr - Warwick (UK) Wrote:[/b]

Phillip's diagnosis on this case is Spitzoid melanoma. I found this case difficult on these images but based on age/site, the fairly obvious pagetoid spread and rather confluent mild cytological atypia (including the dermal component that lacks maturation and includes a rather large nest) are sufficiently disturbing to best regard the whole lesion as a superficial spreading malignant melanoma. Prognosis ought to be excellent as it is thin and lacks dermal mitotic activity. I think this sort of case will always yeild a range of opinion. Apologies for delay and regards to all.

[size=2]Submitted on 08/05/2012 16:11[/size] [b]A Bansal - BCU HB (North Wales) Wrote:[/b]

Dysplastic naevus with severe cytological atypia

[size=2]Submitted on 08/05/2012 11:55[/size] [b]Hazem Hamed - Department of Histopathology, Imperial College (LONDON) Wrote:[/b]

I favour severly dysplastic compound melanocytic nevus.

[size=2]Submitted on 08/05/2012 10:46[/size] [b]Sadiq Mohammed Amer - Al Thawra hospital, Sana'a (Yemen) Wrote:[/b]

Pigmented spindle cell tumor of Reed

[size=2]Submitted on 07/05/2012 19:01[/size] [b]SAMEH ABDEL KODOUS - ALAZHAR UNIVERISTY (CAIRO EGYPT) Wrote:[/b]

ATYPICAL MOLE (DYSPLASTIC N)

[size=2]Submitted on 07/05/2012 18:38[/size] [b]Yüksel Okumuş - Bursa State Hospital (Turkey) Wrote:[/b]

NAD (compound type), severe atypia.

[size=2]Submitted on 07/05/2012 17:34[/size] [b]Engin Sezer - (Istanbul) Wrote:[/b]

Transepidermal elimination of melanin reflects irritation in this melanocytic lesion. Lack of upper migration and presence symmetry and well circumscription (i.e. starting and ending with nests) speaks against melanoma.

[size=2]Submitted on 07/05/2012 17:16[/size] [b]Mona Abdel Halim - () Wrote:[/b]

Severely dysplastic nevus with evolving melanoma

[size=2]Submitted on 07/05/2012 16:41[/size] [b]Juan Carlos Garcés - Hospital Oncológico / Hospital Luis Vernaza (Guayaquil Ecuador) Wrote:[/b]

Compound nevus

[size=2]Submitted on 07/05/2012 16:40[/size] [b]Marwa Fawzy - Dermatology Department, Faculty of Medicine, Cairo University (Egypt) Wrote:[/b]

Severe dysplastic nevus with spitzoid pattern

[size=2]Submitted on 07/05/2012 15:59[/size] [b]Rodrigo Restrepo - UPB/CES (Mdlln/Col) Wrote:[/b]

Melanoma in situ and dysplastic nevus

[size=2]Submitted on 07/05/2012 15:36[/size] [b]Azza Mostafa - (Egypt) Wrote:[/b]

spitzoid melanoma??

[size=2]Submitted on 07/05/2012 14:24[/size] [b]Sasi Attili - (United Kingdom) Wrote:[/b]

Tricky! but would favour Compound dysplasia rather than melanoma

[size=2]Submitted on 07/05/2012 13:58[/size] [b]Eman El-Nabarawy - () Wrote:[/b]

Melanoma.

[size=2]Submitted on 07/05/2012 13:41[/size] [b]Marcela Saeb Lima - INCMNSZ (Mexico City) Wrote:[/b]

melanoma in situ within a compound dysplastic nevus

[size=2]Submitted on 07/05/2012 12:51[/size] [b]Engi Sezer - (Istanbul) Wrote:[/b]

CN with severe cytological and architectural atypia

[size=2]Submitted on 07/05/2012 12:50[/size] [b]Izzat Abdul-kadir - ST2 - York Hospital (UK) Wrote:[/b]

I was undecided at first, largely because of the disorderness of nests. However, the circumscription, symmetry, shouldering, nuclear monomorphism make me think this is simply a compound naevus.

[size=2]Submitted on 07/05/2012 12:42[/size]