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In this section we have spot diagnoses posted on a daily basis since June 2010, now over 4000! You can review the archived cases and read the suggested diagnoses by users and the final comment by the contributors.
Case are uploaded each week day by 10 am UK time with the correct diagnosis will generally be posted at 8 pm UK time. Why not view the most recent spot diagnosis and proffer a diagnosis?

Case Number : Case 634 - 13 Nov Posted By: Guest

Please read the clinical history and view the images by clicking on them before you proffer your diagnosis.
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Male 25 years nodule in axilla.


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Hidradenoma with solid growth pattern

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It seems to be Alveolar soft part sarcoma
the tumor cells are separated by fibrous tissue into well-defined nests, detachment of the central cells results in the typical alveolar pattern. The cells have large vesicular nuclei, prominent nucleoli & a granular cytoplasm. Mitosis is exceptional. PAS demonstrate the intracytoplasmic positive granules
My less likely (bec. of the bland looking cells) d.d. is m melanoma

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Guest Rodrigo Restrepo

Posted

[color=#1C2837][font=arial, verdana, tahoma, sans-serif][size=4]Alveolar soft part sarcoma.[/size][/font][/color]

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Dr. Mona Abdel-Halim

Posted

Agree wit ASPS...great images

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Guest MarieMD

Posted

[b]
[color=#1C2837][font=arial, verdana, tahoma, sans-serif][size=4]Alveolar soft part sarcoma...nice demonstration of crystals in PAS[/size][/font][/color][/b]

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Dr. Phillip McKee

Posted

Well done. Alveolar soft part sarcoma is correct.

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