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In this section we have spot diagnoses posted on a daily basis since June 2010, now over 4000! You can review the archived cases and read the suggested diagnoses by users and the final comment by the contributors.
Case are uploaded each week day by 10 am UK time with the correct diagnosis will generally be posted at 8 pm UK time. Why not view the most recent spot diagnosis and proffer a diagnosis?

Case Number : Case 635 - 14 Nov Posted By: Guest

Please read the clinical history and view the images by clicking on them before you proffer your diagnosis.
Submitted Date :
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Male 45 years, mass right thigh.
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Go to records November 2012

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Guest Dr. Francisco Vílchez

Guest Dr. Francisco Vílchez

Posted

Agree, cutaneous B cell lymphoma, "leg type".

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Guest
Agree with cutaneous B cell lymphoma "leg type"

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Guest Robldo F. Rocha

Guest Robldo F. Rocha

Posted

It´s a dense and diffuse infiltrate of immunoblasts-like neoplastic cells. That means diffuse large B-cell lymphoma, leg-type. This lymphoma is more expected in older women (>70 years of age).

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Sasi Attili

Sasi Attili 85

Posted

I don't quite like the herring bone like pattern in figure 1 and would like to add poorly differentiated sarcoma to the differential of this small blue round cell tumour.

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Dr. Mona Abdel-Halim

Dr. Mona Abdel-Halim 508

Posted

Me too, am not comfortable with the pattern in Fig 1, and also with the clinical presentation as a thigh mass. Would like to suggest peripheral PNET. It usually affect children and young adults but cases in older patients have been reported.

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Iskander H. Chaudhry

Iskander H. Chaudhry 49

Posted

This is a difficult case, but the low-power figure shows a heringbone growth pattern. The final diagnosis is monofazic synovial sarcoma.

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Guest MarieMD

Guest MarieMD

Posted

great case, thought of synovial sarc and PPNET

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