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In this section we have spot diagnoses posted on a daily basis since June 2010, now over 4000! You can review the archived cases and read the suggested diagnoses by users and the final comment by the contributors.
Case are uploaded each week day by 10 am UK time with the correct diagnosis will generally be posted at 8 pm UK time. Why not view the most recent spot diagnosis and proffer a diagnosis?

Case Number : Case 609 - 9 Oct Posted By: Guest

Please read the clinical history and view the images by clicking on them before you proffer your diagnosis.
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Female 18 years with an edematous papule/nodule on the face.


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User Feedback


I think it is cutaneous lymphoid hyperplasia

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Sasi Attili

Posted

Acanthosis/ papillomatosis, some vertical streaking of collagen in the papillary dermis, suggesting a scratch response. However surprisingly can't see much compact orthokeratosis or parakeratosis. The main pathology is a superficial and deep perivascular lymphocytic infiltrate (? wedge shape) with a few eosinophils. ? Insect bite/ pseudolymphoma?

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Guest Guillermo Solis

Posted

Granuloma faciale

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Main diagnosis is lymphocytoma cutis/ B-cutaneous lymphoid hyperplasia

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Lymphoid hyperplasia probably insect bite

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Hanan Vaknine MD

Posted

Insect bite reaction-like picture toped by lichen simplex chronicus-like changes

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Guest Rodrigo Restrepo

Posted

Insect bite

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lymphocytoma cutis/ B-cutaneous lymphoid hyperplasia

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Dr. Phillip McKee

Posted

Well done to all who diagnosed insect bite reaction. This was confirmed by further clinical information. Although cutaneous B-cell lymphoma often enters the differential diagnosis of lymphoid infiltrates, in this case the age of the patient, presentation on the face and the very limited infiltrate all point to an insect bite. Clinicopathological correlation can often lead to an easy resolution of diagostic difficulty and avoid the need for expensive immunohistochemiatry.

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