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In this section we have spot diagnoses posted on a daily basis since June 2010, now over 4000! You can review the archived cases and read the suggested diagnoses by users and the final comment by the contributors.
Case are uploaded each week day by 10 am UK time with the correct diagnosis will generally be posted at 8 pm UK time. Why not view the most recent spot diagnosis and proffer a diagnosis?

Case Number : Case 584 - 4 Sept Posted By: Guest

Please read the clinical history and view the images by clicking on them before you proffer your diagnosis.
Submitted Date :
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Female 60 years with a nodule on the thigh.
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Go to records September 2012

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Guest
I did not see any mitosis, but would consider malignant peripheral nerve sheath tumor

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Dr. Mona Abdel-Halim

Dr. Mona Abdel-Halim 508

Posted

The cells looks atypical, very pleomorphic, there is perivascular accentuation which I have learned from this site that it favors MPNST. So I will consider this as first possibility. Definitely Immunos are mandatory in such case.

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Guest Juan Carlos Garcés, Ecuador

Guest Juan Carlos Garcés, Ecuador

Posted

Ancient Schwannoma / neurofibroma?

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Dr. Phillip McKee

Dr. Phillip McKee 130

Posted

This is another very difficult case. The diagnosis is atypical neurofibroma. The lesion should not be diagnosed in a background of neurofibromatosis. The atypia should be focal and obviously I photographed such fields. Mitoses should be absent or very difficult to find. The lesion should be sporadic. Since connective tissue tumors are not really one of my areas of expertease, I would refer a case such as this to Chris Fletcher for an expert opinion.

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